Results 211 to 220 of about 1,306,106 (344)

Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

EMBO Journal, 1998
M. Takata, M. Sasaki, E. Sonoda, C. Morrison, M. Hashimoto, H. Utsumi, Y. Yamaguchi-Iwai, A. Shinohara, S. Takeda   +8 more
semanticscholar   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Groupthink: chromosomal clustering during transcriptional memory

Microbial Cell, 2015
Kevin A. Morano
doaj   +1 more source

Chromosomal Abnormalities in Couples Experiencing Recurrent Implantation Failure in West of Iran: A Case-Control Study. [PDF]

Mol Genet Genomic Med
Asgari A, Salehi AM, Shahbazi F, Ghahremani S, Saleh EK.   +4 more
europepmc   +1 more source

Physical Location of New PCR-Based Markers and Powdery Mildew Resistance Gene(s) on Rye (Secale cereale L.) Chromosome 4 Using 4R Dissection Lines [PDF]

, 2017
Qiong Duan, Yang Yang Wang, Ling Qiu, Tianheng Ren, Zhi Li, Shouquan Fu, Zong xiang Tang   +6 more
openalex   +1 more source

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Proceedings of the National Academy of Sciences of the United States of America, 2007
R. Beroukhim, G. Getz, L. Nghiemphu, J. Barretina, Teli Hsueh, David Linhart, I. Vivanco, Jeffrey C. Lee, Julie Huang, Sethu Alexander, Jinyan Du, Tweeny R Kau, Roman K. Thomas, K. Shah, H. Soto, S. Perner, John R. Prensner, R. Debiasi, F. Demichelis, C. Hatton, M. Rubin, L. Garraway, S. Nelson, L. Liau, P. Mischel, T. Cloughesy, M. Meyerson, Todd Golub, E. Lander, I. Mellinghoff, W. Sellers   +30 more
semanticscholar   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Familial translocation between chromosomes 3 and 10: meiotic segregation, diagnostics and clinical features of chromosomal imbalance. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Vozilova AV, Tarasova AS, Ivanov EA, Pushkarev VP, Nalyotova NI, Pobedinskaya AI, Sabitova AS, Shilova NV.   +7 more
europepmc   +1 more source

The Mitochondrial Protein RESISTANCE to APHIDS 9 Interacts with S40 to Resist Aphid Infestation by Modulating Reactive Oxygen Species Homeostasis in Maize (Zea mays)

Advanced Science, EarlyView.
This study identifies the mitochondrial protein RTA9, a member of the Domain of Unknown Function 641 family, together with its partner S40, as key regulators of aphid resistance in maize. RTA9 promotes S40 degradation and modulates reactive oxygen species accumulation.
Chuanhong Wang, Xinqiao Zhang, Zhen Tao, Lei Wang, Shijie Huang, Tengyue Wang, Yibing Zhao, Jinghui Dong, Jing Ma, Chang Chang, Xingzhi Chen, Ning Lin, Peijin Li   +12 more
wiley   +1 more source

The role of extrachromosomal DNA in tumorigenesis and progression. [PDF]

Front Oncol
Ma X, Yu X, Wu C, Song L.
europepmc   +1 more source