The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li+3 more
wiley +1 more source
Effective detection of 148 cases chromosomal mosaicism by karyotyping, chromosomal microarray analysis and QF-PCR in 32,967 prenatal diagnoses. [PDF]
Deng Y+9 more
europepmc +1 more source
CROSSING OVER IN THE X CHROMOSOMES OF TRIPLOID FEMALES OF DROSOPHILA MELANOGASTER [PDF]
Calvin B. Bridges, Edgar Anderson
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Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng+11 more
wiley +1 more source
Detecting chromosomal rearrangements in boars using Hi-C. [PDF]
Burden F+5 more
europepmc +1 more source
Studies on chromosomes. II. The paired microchromosomes, idiochromosomes and heterotropic chromosomes in hemiptera [PDF]
Edmund Wilson
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HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou+7 more
wiley +1 more source
Cytogenetic signatures favoring metastatic organotropism in colorectal cancer. [PDF]
Golas MM+8 more
europepmc +1 more source
Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen+9 more
wiley +1 more source
IUGR ambiguous genitalia in Iran: a case report. [PDF]
Shirvani M, Alipour M, Mortajez AR.
europepmc +1 more source