Results 251 to 260 of about 1,274,518 (371)

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

Advanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan, Xueman Chen, Huai Yu, Jianzhao Ruan, Jingliang Kang, Xiaoyu Nie, Yumei Cao, Su'an Tang, Changhai Ding   +8 more
wiley   +1 more source

Elimination of Chromosomes Due to a Mutant (Minute-N) in Drosophila Melanogaster [PDF]

, 1925
Calvin B. Bridges
openalex   +1 more source

Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system

Nature Communications, 2014
R. Torres, M. C. Martin, Ana García, J. Cigudosa, J. Ramírez, S. Rodríguez-Perales   +5 more
semanticscholar   +1 more source

Chromosomal passengers [PDF]

Current Biology, 2001
openaire   +2 more sources

Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas

Advanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian, Shuqin Liu, Hongtao Shi, Jianjun Li, Xinglong Wan, Yujiang Sun, Huayun Li, Ning Cao, Zhixi Feng, Teng Zhang, Junjie Wang, Wei Shen   +11 more
wiley   +1 more source

Prenatal diagnosis and molecular cytogenetic analyses of a rare 15q21.3 and 16p11.2 microduplication family. [PDF]

Mol Cytogenet
Zhang F, Liao G, Wen X, Zhang C.
europepmc   +1 more source

Genetical behavior of heteromorphic homologous chromosomes of circotettix (Orthoptera) [PDF]

, 1921
E. Eleanor Carothers
openalex   +1 more source

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia   +19 more
wiley   +1 more source

Outcomes associated with fetal nuchal translucency between 3.0 and 3.4 mm in the first trimester. [PDF]

Acta Obstet Gynecol Scand
Vriendt MDE, Rooryck C, Madar H, Coatleven F, Vincienne M, Prier P, Naudion S, Sentilhes L, Bouchghoul H.   +8 more
europepmc   +1 more source

A Model of Epigenetic Inheritance Accounts for Unexpected Adaptation to Unforeseen Challenges

Advanced Science, EarlyView.
A general model of inheriting changes that are acquired during the lifetime of individuals demonstrates tremendous benefits to the population, including escape from extinction in changing environments. Contrasting the model with experimental data shows that inheritance of acquired changes enables rapid adaptation to unforeseen challenges, and accounts ...
Dino Osmanović, Yitzhak Rabin, Yoav Soen   +2 more
wiley   +1 more source