Results 301 to 310 of about 1,306,106 (344)
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Screening for Fetal Chromosomal Abnormalities.
Obstetrics and Gynecology, 2020Prenatal testing for chromosomal abnormalities is designed to provide an accurate assessment of a patient's risk of carrying a fetus with a chromosomal disorder. A wide variety of prenatal screening and diagnostic tests are available; each offers varying
N. Rose, A. Kaimal, L. Dugoff, M. Norton
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Chromosome imprinting and the mammalian X chromosome [PDF]
Nature, 1975 Chromosome imprinting is the process by which one of two genetically homologous chromosomes is predetermined to function differently from the other at a subsequent stage in development. In the coccid insects, imprinting occurs in the egg, at the time of fertilisation; it probably occurs at the same time and site in mammals, and possibly also in Sciara.
Spencer W. Brown, H. Sharat Chandra
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Cytogenetic and Genome Research, 2005
The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
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The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
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Current Opinion in Oncology, 2004
This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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Journal of Cell Science, 1977
ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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Nature, 1966
RECENTLY, I carried out chromosome analyses and sex chromatin determinations on ten patients—five females and five males—between 63 and 91 years old. The organic status of these individuals was variable, and all were ill in some way. Nevertheless, the results obtained in this investigation were reasonably uniform; their chromosomes and Barr bodies ...
W. M. Court Brown, Patricia A. Jacobs
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RECENTLY, I carried out chromosome analyses and sex chromatin determinations on ten patients—five females and five males—between 63 and 91 years old. The organic status of these individuals was variable, and all were ill in some way. Nevertheless, the results obtained in this investigation were reasonably uniform; their chromosomes and Barr bodies ...
W. M. Court Brown, Patricia A. Jacobs
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The human Y chromosome: a masculine chromosome
Current Opinion in Genetics & Development, 2006Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production.
Michiel J. Noordam, Sjoerd Repping
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The Duplication of Chromosomes
Scientific American, 1958Chromosome duplication first of all requires the replication of the DNA. It is now clear that the replication of most if not all of the chromosomal DNA follows the scheme based on precise base pairing as originally proposed by Watson and Crick [50].
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JAMA: The Journal of the American Medical Association, 1970
To the Editor.— Tjio et al (210:849, 1969) have made an important methodological advance in the study of the effects of lysergic acid diethylamide (LSD) on human chromosomes in vivo by measuring chromosome aberration rates in subjects both before and after LSD administration. The authors were unable to conclude that LSD had a harmful effect.
Jerome H. Klotz, Etan Markowitz
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To the Editor.— Tjio et al (210:849, 1969) have made an important methodological advance in the study of the effects of lysergic acid diethylamide (LSD) on human chromosomes in vivo by measuring chromosome aberration rates in subjects both before and after LSD administration. The authors were unable to conclude that LSD had a harmful effect.
Jerome H. Klotz, Etan Markowitz
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