Results 311 to 320 of about 1,274,518 (371)

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

open access: yesAdvanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian   +5 more
wiley   +1 more source

Fetal Hydrops: Genetic Dissection of an Unspecific Sonographic Finding-A Comprehensive Review. [PDF]

open access: yesDiagnostics (Basel)
Mastromoro G   +4 more
europepmc   +1 more source

Rational Design and Organoid‐Based Evaluation of a Cocktail CAR‐γδ T Cell Therapy for Heterogeneous Glioblastoma

open access: yesAdvanced Science, EarlyView.
A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu   +12 more
wiley   +1 more source

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng   +9 more
wiley   +1 more source

Evaluation of Clastogenic and Aneugenic Action of Two Bio-Insecticides Using Allium Bioassay. [PDF]

open access: yesJ Xenobiot
Duta-Cornescu G   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy