Results 51 to 60 of about 342,458 (306)
BMC Evolutionary Biology, 2020 Background Chromosomal rearrangements are thought to be an important driving force underlying lineage diversification, but their link to speciation continues to be debated.
Juliette Auvinet +8 more
doaj +1 more source
Karyotypes of the Mole Rats, genus Nannospalax (Palmer, 1903) (Spalacidae: Rodentia) populations in eastern Anatolia, Turkey [PDF]
Iranian Journal of Animal Biosystematics, 2012 The Spalacidae are Southeast European and East Mediterranean blind rodents, highly adapted for life underground. Their taxonomy needs a modern revision including chromosomal data as well as morphology. Mole rats of the family Spalacidae range over Turkey
Y Coşkun +4 more
doaj +1 more source
, 2004 OBJECTIVES: To assess whether the offspring of UK veterans of the first Gulf war are at increased risk of fetal death or congenital malformation. METHOD: This was a retrospective reproductive cohort study of UK Gulf war veterans and a demographically ...
Davies, Graham +6 more
core +1 more source
Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization [PDF]
, 1990 Chromosomal in situ suppression (CISS)-hybridization of biotinylated phage DNA-library inserts from sorted human chromosomes was used to decorate chromosomes 1 and 7 specifically from pter to qter and to detect structural aberrations of these chromosomes
Cremer, Christoph +4 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Whole-Exome Sequencing Study of Thyrotropin-Secreting Pituitary Adenomas [PDF]
, 2018 学位記番号 ...
Santosh, Sapkota +2 more
core
Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11 [PDF]
, 2005 Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional ...
De Preter, K +13 more
core +3 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
A new species in the major malaria vector complex sheds light on reticulated species evolution [PDF]
, 2019 Complexes of closely related species provide key insights into the rapid and independent evolution of adaptive traits. Here, we described and studied Anopheles fontenillei sp.n., a new species in the Anopheles gambiae complex that we recently discovered ...
Akone-Ella O. +11 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source