Results 151 to 160 of about 92,178 (328)

Oogenesis and germinal bed morphology of the brown anole (A. sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher, Antonia Weberling, Erin J. Vance, Natalia A. Shylo, Katherine Starr, Zoe B. Griffin, Hannah Wilson, Melainia McClain, Florian Hollfelder, Suzannah A. Williams, Thomas J. Sanger, Richard R. Behringer, Paul A. Trainor   +12 more
wiley   +1 more source

Identification of a familial complex chromosomal rearrangement by optical genome mapping. [PDF]

Mol Cytogenet, 2022
Yang Y, Hao W.
europepmc   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

The canonical non-homologous end joining factor XLF promotes chromosomal deletion rearrangements in human cells [PDF]

, 2019
Ragini Bhargava, Felicia Wednesday Lopezcolorado, Linda Jillianne Tsai, Jeremy M. Stark   +3 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Rare 15q21.1q22.31 Duplication Due to a Familial Chromosomal Insertion and Diagnostic Investigation in a Carrier of Balanced Chromosomal Rearrangement and Intellectual Disability. [PDF]

Genes (Basel), 2023
Nascimento CG, Prota JRM, Sgardioli IC, Spineli-Silva S, Campos NLV, Gil-da-Silva-Lopes VL, Vieira TP.   +6 more
europepmc   +1 more source

Cervical Angiomatoid Fibrous Histiocytoma [PDF]

, 2012
Background: Angiomatoid fibrous histiocytoma (AFH) is a rare type of sarcoma with low-grade malignancy thatusually occurs in young subjects. AFH is uncommon in the head and neck region.Methods: We describe an exceptional case of localization in the neck.
Arnaud, Sebestian, Barosa, Joao, Felasi, Mohammad Al, Makeieff, Marc   +3 more
core   +1 more source

The evolution of vertebrate somatostatin receptors and their gene regions involves extensive chromosomal rearrangements [PDF]

, 2012
Daniel Ocampo Daza, Görel Sundström, Christina A Bergqvist, Dan Larhammar   +3 more
openalex   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

GraphChrom: A Novel Graph-Based Framework for Cancer Classification Using Chromosomal Rearrangement Endpoints. [PDF]

Cancers (Basel), 2022
Mirzaei G.
europepmc   +1 more source