Long-read Oxford nanopore sequencing reveals a de novo case of complex chromosomal rearrangement involving chromosomes 2, 7, and 13. [PDF]
Mol Genet Genomic Med, 2022 Xing L +6 more
europepmc +1 more source
Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer [PDF]
, 2019 Qian Du +13 more
openalex +1 more source
The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia
International Journal of Cancer, EarlyView.Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch +5 more
wiley +1 more source
Molecular analysis of a constitutional complex genome rearrangement with 11 breakpoints involving chromosomes 3, 11, 12, and 21 and a ∼0.5-Mb submicroscopic deletion in a patient with mild mental retardation [PDF]
, 2005 Katarzyna Borg +6 more
openalex +1 more source
Charm is a flexible pipeline to simulate chromosomal rearrangements on Hi-C-like data [PDF]
, 2023 Miroslav Nuriddinov +2 more
openalex +1 more source
iMetaOmics, EarlyView.A new bioinformatics pipeline called ECCFP has been developed to improve the detection of extrachromosomal circular DNA (eccDNA) from long‐read sequencing data. ECCFP uses all consecutive full passes from individual reads for candidate eccDNA identification and consolidates candidate eccDNAs to generate accurate unique eccDNA.
Wang Li +14 more
wiley +1 more source
Identification of Balanced and Unbalanced Complex Chromosomal Rearrangement Involving Chromosomes 1, 11, and 15. [PDF]
Cureus, 2021 Vafaeie F +3 more
europepmc +1 more source
Karyotype Diversification and Chromosome Rearrangements in Squamate Reptiles [PDF]
Marcello Mezzasalma +3 more
openalex +1 more source