Results 181 to 190 of about 92,178 (328)

Fast bootstrap and reliable readout using hidden references for DNA data storage

iMeta, EarlyView.
This study provides a bootstrap readout framework for DNA data storage based on multiple‐fold hidden references. We employ a multi‐stage alignment and error correction strategy, transforming the de novo readout into a resequencing‐like workflow. Correlation to the hidden watermark reference identifies low‐error‐rate reads, and bit‐wise consensus ...
Weigang Chen, Shuang Liu, Quan Guo, Rui Qin, Qi Ge, Tingting Qi, Yingjin Yuan   +6 more
wiley   +1 more source

Rapid reconstruction of reference chromosome-level mammalian genome assemblies and insight into the mechanisms of gross genomic rearrangement - BBSRC

, 2018
Darren K. Griffin
openalex   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

Extensive Pericentric Rearrangements in the Bread Wheat ( Triticum aestivum L.) Genotype “Chinese Spring” Revealed from Chromosome Shotgun Sequence Data [PDF]

, 2014
Jian Ma, Jiri Stiller, Yuming Wei, Youliang Zheng, Katrien M. Devos, Jaroslav Doležel, Chunji Liu   +6 more
openalex   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Classification of genes, rearrangements and chromosomes according to the chromosome field [PDF]

, 2009
A. Lima-de-Faria
openalex   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Interstitial telomeric sequences promote gross chromosomal rearrangement via multiple mechanisms. [PDF]

Proc Natl Acad Sci U S A
Rosas Bringas FR, Yin Z, Yao Y, Boudeman J, Ollivaud S, Chang M.   +5 more
europepmc   +2 more sources

Mendelian and non-Mendelian inheritance of newly-arisen chromosome rearrangements [PDF]

, 1988
A S Wilby, Joe Parker
openalex   +1 more source