Results 301 to 310 of about 92,178 (328)
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Engineering chromosomal rearrangements in mice
Nature Reviews Genetics, 2001The combination of gene-targeting techniques in mouse embryonic stem cells and the Cre/loxP site-specific recombination system has resulted in the emergence of chromosomal-engineering technology in mice. This advance has opened up new opportunities for modelling human diseases that are associated with chromosomal rearrangements.
Y, Yu, A, Bradley
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Structural Chromosome Rearrangements
1999The subject of structural chromosome rearrangements is an immense one, to which entire catalogs have been devoted. Indeed, there are theoretically an almost infinite number of ways in which chromosomes can reconfigure themselves from the normal 23-pair arrangement with which we are familiar.
Kathleen Kaiser-Rogers, Kathleen Rao
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2007
X chromosome rearrangements usually convey clinical manifestations in the hemizygous males and are, thus, readily ascertained. They are found in all parts of the X chromosome and are associated with more than 20 disorders. Some of the rearrangements are the results of homologous recombination between low-copy repeats (LCRs) on the X chromosome or ...
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X chromosome rearrangements usually convey clinical manifestations in the hemizygous males and are, thus, readily ascertained. They are found in all parts of the X chromosome and are associated with more than 20 disorders. Some of the rearrangements are the results of homologous recombination between low-copy repeats (LCRs) on the X chromosome or ...
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Chromosomal Rearrangements and Mental Retardation
Pediatric Research, 2000A review of: Knight SJL, Regan R, Nicod A, et al. 1999 Subtle Chromosomal Rearrangements in Children with Unexplained Mental Retardation. Lancet 354:1676–1681.
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Balanced Chromosome Rearrangements
2006Abstract Balanced chromosome rearrangements are those in which there is no overall loss or gain of chromosome material. Unlike single-gene disorders, for which precise calculation of risks to offspring is usually possible, the segregation of chromosome rearrangements does not readily conform to any mathematical model that permits exact ...
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Chromosome rearrangements in Giardia lamblia
Parasitology Today, 1994Recent studies have shown that the genome of Giardia lamblia is plastic. Clinical isolates exhibit extensive karyotypic heterogeneity and chromosome rearrangements occur frequently, in vitro. In this review, Sylvie Le Blancq looks at genome organization and the impact of DNA rearrangement events.
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Balanced chromosome rearrangements
1991Abstract Balanced chromosome rearrangements are those in which there is no overall loss or gain of chromosome material. Unlike single gene disorders for which precise calculation of risks to offspring is usually possible, the segregation of chromosome rearrangements does not readily conform to any mathematical model which permits exact ...
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Complex chromosomal rearrangements.
Genetic counseling (Geneva, Switzerland), 2007Complex Chromosomal Rearrangements (CCRs) are constitutional structural rearrangements involving three or more chromosomes or having more than two breakpoints. CCRs preferentially occur during spermatogenesis and are transmitted in families through oogenesis.
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Rearrangements of Chromosome Segments
1998• Inversions rearrange segments within or between arms of single chromosomes, whereas reciprocal translocations exchange segments between chromosomes. • Inversions and translocations can be detected by changes in mitotic chromosome structure and by distinctive meiotic configurations.
Rudi Appels +3 more
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Chromosomal rearrangements and speciation
Trends in Microbiology, 2000Reproductive isolation in the Saccharomyces genus is the result of post-zygotic barriers, as many species mate successfully but the hybrids are sterile. To test whether chromosomal rearrangements were the cause of reproductive isolation (and therefore speciation) in yeast, Fischer et al.1xChromosomal evolution in Saccharomyces. Fischer, G.
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