An intra-chromosomal translocation inserts a 1.35 megabase DNA fragment into the chromosome 7Q34-Q36.2 DHMN1 locus [PDF]
, 2016 Alexander P. Drew +4 more
openalex
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
[APL-like leukemia with chromosomal translocation t(16;17): a case report and literature review]. [PDF]
Zhonghua Xue Ye Xue Za ZhiWang Q, Lyu TX, Ai H, Lyu XD, Yin QS.
europepmc +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Chromosomes and causation of human cancer and leukemia. XXIV. Unusual and complex Ph1 translocations and their clinical significance [PDF]
, 1977 SI Sonta, AA Sandberg
openalex +1 more source
Ultrasound in Obstetrics &Gynecology, EarlyView.ABSTRACT Objective To investigate whether combining abnormal morphological features observed on ultrasound in live pregnancies that ended in a first‐trimester miscarriage can predict an abnormal karyotype. Methods This retrospective observational cohort study was conducted at the early‐pregnancy assessment unit at University College London Hospital ...
T. Setty +5 more
wiley +1 more source
PARP1 is required for chromosomal translocations [PDF]
, 2013 Justin Wray +14 more
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AMHR2 mutation in persistent Müllerian duct syndrome: A case of transverse testicular ectopia
UroPrecision, EarlyView.Abstract Backgroud Persistent Müllerian duct syndrome (PMDS) is a rare condition characterized by the persistence of Müllerian duct structures in genotypic and phenotypic males. Case Presentation We present the case of a 4‐month‐old male with PMDS who presented with transverse testicular ectopia. The patient underwent diagnostic laparoscopic orchiopexy
Hangcheng Fu +2 more
wiley +1 more source
Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model [PDF]
, 2015 Miwa Tanaka +8 more
openalex +1 more source
Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones
The Journal of Dermatology, EarlyView.ABSTRACT Mycosis fungoides (MF) is a unique type of lymphoma with an excellent prognosis presenting with a wide variety of clinical and histological findings. Recent sophisticated research techniques have revealed that very slow changes in the clinical and histological pictures of one patient over time are due to intratumoral heterogeneity.
Ryoma Honda +2 more
wiley +1 more source