Results 181 to 190 of about 158,249 (312)

Three annotated chromosome-level de novo genome assemblies of Lomentospora prolificans provide evidence for a chromosomal translocation event. [PDF]

G3 (Bethesda)
Grossman NT, Fan Y, Zimin AV, Wear MP, Jedlicka A, Dziedzic A, Liporagi-Lopes LC, Timp W, Casadevall A.   +8 more
europepmc   +1 more source

Association between serum α‐Klotho levels and severity of periodontitis in a representative U.S. population

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α‐Klotho, an anti‐aging protein with anti‐inflammatory properties, has been associated with systemic diseases, but its role in periodontitis is unclear.
Hamoun Sabri, Sahar Baniameri, Pranav Kataria, Hend Abulatifa, Parham Hazrati, Hom‐Lay Wang, Muhammad H. A. Saleh   +6 more
wiley   +1 more source

The RNA tether model for human chromosomal translocation fragile zones. [PDF]

Trends Biochem Sci
Liu D, Hsieh CL, Lieber MR.
europepmc   +1 more source

Dynamic Profiling of Circulating Tumor Cells and MYC/PTEN Alterations in Prostate Cancer Patients Undergoing Radical Prostatectomy in Amazon Population

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed malignancy among men and the sixth leading cause of cancer‐related mortality worldwide. Radical prostatectomy remains the standard treatment for localized disease; however, approximately one‐third of patients develop biochemical recurrence within 10 years. Although prostate‐specific
Juliana Ramos Chaves, Rommel Mario Rodriguez Burbano, Amanda de Nazaré Cohen‐Paes, Diego Di Felipe Ávila Alcântara, Ana Paula Borges de Souza, Maria Janete Nahum Gomes, Sérgio Augusto Antunes Ramos, André Salim Khayat   +7 more
wiley   +1 more source

Coexistence of acute myeloid leukemia with a complex chromosomal translocation and monoclonal gammopathy of undetermined significance: A case report and literature review. [PDF]

Oncol Lett
Qiao X, Geng L, Tian T, Zhang J, Guo X, Qiao S.   +5 more
europepmc   +1 more source

Application of Chromosome Conformation Capture Method for Detection MYC/TRD Chromosomal Translocation in Leukemia Cell Line. [PDF]

Int J Hematol Oncol Stem Cell Res, 2020
Absalan M, Ghahremani MH, Jabbarpour Z, Karimi R, Shafei S, Heidari R, Akbariqomi M, Tavoosidana G.   +7 more
europepmc   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia, leads to RCC1::IRF4 fusion. [PDF]

Br J Haematol
Jayne S, López C, Put N, Nagel I, Lierman E, Penas EMM, Michaux L, Ahearne MJ, Walter HS, Bens S, Drewes C, Szczepanowski M, Schlesner M, Rosenstiel P, Wlodarska I, Siebert R, Dyer MJS.   +16 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Altered chromatin topologies caused by balanced chromosomal translocation lead to central iris hypoplasia. [PDF]

Nat Commun
Sun W, Xiong D, Ouyang J, Xiao X, Jiang Y, Wang Y, Li S, Xie Z, Wang J, Tang Z, Zhang Q.   +10 more
europepmc   +1 more source