Results 241 to 250 of about 982,148 (390)

The RNA tether model for human chromosomal translocation fragile zones. [PDF]

Trends Biochem Sci
Liu D, Hsieh CL, Lieber MR.
europepmc   +1 more source

Homologous alpha satellite sequences on human acrocentric chromosomes with selectivity for chromosomes 13, 14 and 21: implications for recombination between nonhomologues and Robertsonian translocations [PDF]

, 1988
K. H. Andy Choo, Bryce Vissel, Robert Brown, R. GAY FILBY, Elizabeth D. Earle   +4 more
openalex   +1 more source

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

International Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville, Lisa J. Russell, Kay Padget, Akram Ghantous, Jessica Nordlund, Jill A. McKay   +5 more
wiley   +1 more source

The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia, leads to RCC1::IRF4 fusion. [PDF]

Br J Haematol
Jayne S, López C, Put N, Nagel I, Lierman E, Penas EMM, Michaux L, Ahearne MJ, Walter HS, Bens S, Drewes C, Szczepanowski M, Schlesner M, Rosenstiel P, Wlodarska I, Siebert R, Dyer MJS.   +16 more
europepmc   +1 more source

Fusion of the COL4A5 Gene With NR2F2-AS1 in a Hemangioma Carrying a t(X;15)(q22;q26) Chromosomal Translocation. [PDF]

Cancer Genomics Proteomics, 2020
Panagopoulos I, Gorunova L, Lobmaier I, Andersen K, Lund-Iversen M, Micci F, Heim S.   +6 more
europepmc   +1 more source

Molecular detection of chromosomal translocations that disrupt the putative retinoblastoma susceptibility locus. [PDF]

, 1989
Michael J. Higgins, Mark Hansen, Webster K. Cavenee, M. Lalande   +3 more
openalex   +1 more source

CD86, the double agent: Significance of CD86 expression in B‐cell malignancies

International Journal of Cancer, EarlyView.
Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Gábor Barna, Gábor Szalóki, Ágnes Márk, Anna Hunyadi, Csilla Kriston   +4 more
wiley   +1 more source

Prader-Willi syndrome in siblings, due to unbalanced translocation between chromosomes 15 and 22. [PDF]

, 1987
Francisca Fernandez, Colin Berry, David Mutton   +2 more
openalex   +1 more source

Extrachromosomal Circular DNA: Emerging Insights Into Cardiovascular Disease Mechanisms and Biomarker Potential

iLABMED, EarlyView.
Extrachromosomal circular DNA (eccDNA) has quite recently turned out to be a cardinal component in cardiovascular diseases (CVD), governing the gene expression and mechanisms of disease causation. Studies indicated an upregulation of eccDNA in pulmonary arterial hypertension (PAH), which makes it strikingly potential as a sensitive and specific ...
Saim Mahmood Khan, Jawairya Muhammad Hussain, Surraiya Riaz Mahmood Khan, Bushra Nadeem, Tahniyat Naseem, Hammad Jawed, Aina Lashari   +6 more
wiley   +1 more source

Identification of allelic relationship and translocation region among chromosomal translocation lines that leads to less-seed watermelon. [PDF]

Hortic Res
Jiao D, Zhao H, Sun H, Zhang J, Zhang H, Gong G, Anees M, Zhu H, Liu W, Xu Y.   +9 more
europepmc   +1 more source