A cluster of chromosome 11p13 translocations found via distinct D-D and D-D-J rearrangements of the human T cell receptor delta chain gene. [PDF]
Thomas Boehm+4 more
openalex +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
Hunter's disease in a girl: association with X:5 chromosomal translocation disrupting the Hunter gene. [PDF]
Jim A. Mossman+4 more
openalex +1 more source
ABSTRACT The current study aims to delineate the role of a novel anaplastic lymphoma kinase (ALK) transcript, ALKATI, in ovarian high‐grade serous carcinoma (HGSC). Overexpressed ALKATI exhibited both cytoplasmic and nuclear localization in HGSC cells, whereas full‐length ALK was predominantly cytoplasmic.
Ako Yokoi+4 more
wiley +1 more source
Acute leukemias associated with the 4;11 chromosome translocation have rearranged immunoglobulin heavy chain genes [PDF]
WM Crist+8 more
openalex +1 more source
Recent Advancements in the Treatment of Age‐Related Macular Degeneration
ABSTRACT Age‐related macular degeneration (AMD) is a prevalent cause of visual impairment and blindness among the elderly. AMD can be categorized into two subtypes: “wet” and “dry.” Current treatments for wet AMD mainly involve anti‐vascular endothelial growth factor (VEGF) drugs, and there are three U.S.
Shan Liu+10 more
wiley +1 more source
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García+4 more
wiley +1 more source
Moderate-Level Gene Amplification in Methotrexate-Resistant Chinese Hamster Ovary Cells is Accompanied by Chromosomal Translocations At or Near the Site of the Amplified DHFR Gene [PDF]
Wayne F. Flintoff+3 more
openalex +1 more source
Upper respiratory tract carcinoma with chromosomal translocation 15;19
S. Vargas+6 more
semanticscholar +1 more source