Results 261 to 270 of about 982,148 (390)

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Hunter's disease in a girl: association with X:5 chromosomal translocation disrupting the Hunter gene. [PDF]

open access: bronze, 1983
Jim A. Mossman   +4 more
openalex   +1 more source

A Transcriptional Variant of Anaplastic Lymphoma Kinase Promotes Apoptosis in Ovarian High‐Grade Serous Carcinoma

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT The current study aims to delineate the role of a novel anaplastic lymphoma kinase (ALK) transcript, ALKATI, in ovarian high‐grade serous carcinoma (HGSC). Overexpressed ALKATI exhibited both cytoplasmic and nuclear localization in HGSC cells, whereas full‐length ALK was predominantly cytoplasmic.
Ako Yokoi   +4 more
wiley   +1 more source

Acute leukemias associated with the 4;11 chromosome translocation have rearranged immunoglobulin heavy chain genes [PDF]

open access: bronze, 1985
WM Crist   +8 more
openalex   +1 more source

Recent Advancements in the Treatment of Age‐Related Macular Degeneration

open access: yesMed Research, EarlyView.
ABSTRACT Age‐related macular degeneration (AMD) is a prevalent cause of visual impairment and blindness among the elderly. AMD can be categorized into two subtypes: “wet” and “dry.” Current treatments for wet AMD mainly involve anti‐vascular endothelial growth factor (VEGF) drugs, and there are three U.S.
Shan Liu   +10 more
wiley   +1 more source

Neuroprotective Potential of the Flavonoids Quercetin and Epicatechin in a C. elegans Tauopathy Model

open access: yesMolecular Nutrition &Food Research, EarlyView.
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García   +4 more
wiley   +1 more source

Upper respiratory tract carcinoma with chromosomal translocation 15;19

open access: yesCancer, 2001
S. Vargas   +6 more
semanticscholar   +1 more source

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