Results 151 to 160 of about 115,560 (292)

Synapsis-Defective Mutants Reveal a Correlation Between Chromosome Conformation and the Mode of Double-Strand Break Repair DuringCaenorhabditis elegansMeiosis [PDF]

, 2007
Sarit Smolikov, Andreas Eizinger, Allison Hurlburt, Eric Rogers, Anne M. Villeneuve, Mónica P. Colaiácovo   +5 more
openalex   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

The Dynamics of the ESCRT Machinery in Open Mitosis from Physiology to Pathology. [PDF]

Cells
La Torre M, Cannistrà F, Burla R, Saggio I.   +3 more
europepmc   +1 more source

Defective histone supply causes condensin-dependent chromatin alterations, SAC activation and chromosome decatenation impairment [PDF]

, 2016
Marina Murillo-Pineda, María J. Cabello-Lobato, Marta Clemente‐Ruiz, Fernando Monje-Casas, Félix Prado   +4 more
openalex   +1 more source

Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs

Cancer Science, EarlyView.
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi, Rubaiat E. Tabassum, Kouji Hirota   +2 more
wiley   +1 more source

HEIP1 orchestrates pro-crossover protein activity during mammalian meiosis. [PDF]

Proc Natl Acad Sci U S A
De Muyt A, Lee S, Khanal S, Dal Toe L, Adam C, Mercier R, Borde V, Hunter N, Robert T.   +8 more
europepmc   +1 more source

TREX2 exonuclease defective cells exhibit double-strand breaks and chromosomal fragments but not Robertsonian translocations

, 2008
Lavinia C. Dumitrache, Lingchuan Hu, Paul Hasty   +2 more
openalex   +1 more source

A Novel Homozygous Nonsense Pathogenic Variant of the CPAMD8 Gene Associated With Congenital Microcoria

Clinical Genetics, EarlyView.
A novel CPAMD8 nonsense mutation c.2679C>G (p.Tyr893*) was identified in a patient with congenital microcoria, leading to reduced mRNA expression and predicted protein truncation. ABSTRACT Congenital microcoria (MCOR) is a rare inherited ocular disorder. Here, we describe a novel nonsense variant in the CPAMD8 gene in a patient with MCOR.
Jing‐Fan Gao, Xin Jin, Jing‐Rao Wang, Shu Wang, Hong Zhang   +4 more
wiley   +1 more source

Eph-ephrin signaling and its potential role in female reproductive tract development. [PDF]

Mol Biol Rep
Prasun P.
europepmc   +1 more source

Defective Rad51 focus formation and spontaneous chromosomal aberrations in mutant cells

, 2011
Hinz John M., S. Tebbs Robert, F. Wilson Paul, Beate Peter, P. Salazar Edmund, Hatsumi Nagasawa, S. Urbin Salustra, S. Bedford Joel, H. Thompson Larry   +8 more
openalex   +1 more source