Results 21 to 30 of about 115,560 (292)

Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation

eLife, 2013
The X-chromosome gene regulatory process called dosage compensation ensures that males (1X) and females (2X) express equal levels of X-chromosome transcripts.
William S Kruesi, Leighton J Core, Colin T Waters, John T Lis, Barbara J Meyer   +4 more
doaj   +1 more source

Triple-Marker Prenatal Screening Program for Chromosomal Defects

Obstetrics & Gynecology, 2009
To examine screening performance of California's triple-marker screening program, using data from a statewide registry for chromosomal defects.This study included 752,686 women who received a screening risk and had an expected date of delivery between July 2005 and the end of June 2007.
Kazerouni, N. Neely, Currier, Bob, Malm, Linda, Riggle, Susan, Hodgkinson, Christina, Smith, Sylvia, Tempelis, Corinna, Lorey, Fred, Davis, Amber, Jelliffe-Pawlowski, Laura, Walton-Haynes, Lynn, Roberson, Marie   +11 more
  +8 more sources

An Autosomal Translocation 73,XY,t(12;20)(q11;q11) in an Infertile Male Llama (Lama glama) With Teratozoospermia

Frontiers in Genetics, 2019
Structural chromosome abnormalities, such as translocations and inversions occasionally occur in all livestock species and are typically associated with reproductive and developmental disorders.
Malorie P. Baily, Felipe Avila, Pranab J. Das, Michelle A. Kutzler, Terje Raudsepp   +4 more
doaj   +1 more source

Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis

Cell Reports
Summary: Mitotic chromosomes oscillate between the spindle poles upon the establishment of bi-orientation, which is essential for chromosome alignment and subsequent synchronous segregation.
Chengcheng Hu, Qing Hu, Tongtong Yang, Panpan Xu, Fangyuan Xiong, Xinyang Wang, Chao Wang, Kai Jiang, Donald L. Hill, Lin Xue, Changlu Tao, Chuanhai Fu, Liang Zhang, Dan Liu, Shengqi Xiang, Jianye Zang, Zhikai Wang, Xuebiao Yao, Xing Liu   +18 more
doaj   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Dot1-dependent histone H3K79 methylation promotes the formation of meiotic double-strand breaks in the absence of histone H3K4 methylation in budding yeast.

PLoS ONE, 2014
Epigenetic marks such as histone modifications play roles in various chromosome dynamics in mitosis and meiosis. Methylation of histones H3 at positions K4 and K79 is involved in the initiation of recombination and the recombination checkpoint ...
Mohammad Bani Ismail, Miki Shinohara, Akira Shinohara   +2 more
doaj   +1 more source

Chromosomal defects in multiple myeloma

Blood Reviews
Multiple myeloma is a plasma cell neoplasm driven by primary (e.g. hyperdiploidy; IGH translocations) and secondary (e.g. 1q21 gains/amplifications; del(17p); MYC translocations) chromosomal events. These are important to detect as they influence prognosis, therapeutic response and disease survival.
Sarah E, Clarke, Kathryn A, Fuller, Wendy N, Erber   +2 more
openaire   +2 more sources

Nicotine-induced Disturbances of Meiotic Maturation in Cultured Mouse Oocytes: Alterations of Spindle Integrity and Chromosome Alignment

Tobacco Induced Diseases, 2004
We investigated whether nicotine exposure in vitro of mouse oocytes affects spindle and chromosome function during meiotic maturation (M-I and M-II). Oocytes in germinal vesicle (GV) stage were cultured in nicotine for 8 h or for 16 h, to assess effects ...
Maria Teresa Zenzes, Ryszard Bielecki
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Screening for chromosomal defects

Sri Lanka Journal of Obstetrics and Gynaecology, 2012
DOI: http://dx.doi.org/10.4038/sljog.v33i3.4023 Sri Lanka Journal of Obstetrics and Gynaecology 2011; 33 : 124 ...
openaire   +2 more sources