Results 151 to 160 of about 1,768,096 (341)
Cytogenomic evaluation of regenerated Aralia elata using PLOP-FISH and flow cytometry
Aralia elata is closely related to Panax ginseng and contains high levels of saponins and other medicinal compounds. Successful A. elata micropropagation is commercially significant; however, the genomic stability of tissue culture-derived regenerants is
Eliazar Alumbro Peniton+4 more
doaj +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini+13 more
wiley +1 more source
Maximizing meiotic crossover rates reveals the map of Crossover Potential
Sexual dysmorphism in the number and distribution of meiotic crossovers is seen across species but is poorly understood. Here, we disrupt multiple anti-crossover pathways in hermaphrodite Arabidopsis and analyze thousands of female and male progeny ...
Juli Jing+3 more
doaj +1 more source
Microscopes and computers combined for analysis of chromosomes [PDF]
Scanning machine CHLOE, developed for photographic use, is combined with a digital computer to obtain quantitative and statistically significant data on chromosome shapes, distribution, density, and pairing.
Butler, J. W.+2 more
core +1 more source
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla+13 more
wiley +1 more source
Cryo-EM single-particle analyses typically require target macromolecule concentration at 0.05~5.0 mg/ml, which is often difficult to achieve. Here, we devise Magnetic Isolation and Concentration (MagIC)-cryo-EM, a technique enabling direct structural ...
Yasuhiro Arimura+2 more
doaj +1 more source
THE CYTOLOGICAL IDENTIFICATION OF THE CHROMOSOME ASSOCIATED WITH THE R-G LINKAGE GROUP IN ZEA MAYS [PDF]
Barbara McClintock, Henry E. Hill
openalex +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers+10 more
wiley +1 more source
Elimination of Chromosomes during Cleavage in the Eggs of Sciara (Diptera) [PDF]
Anne Marie DuBois
openalex +1 more source