Results 161 to 170 of about 1,659,623 (343)

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li   +8 more
wiley   +1 more source

A survey of chromosome anomalies in Malta [PDF]

open access: yes, 1989
433 individuals referred for chromosome analysis between 1983 and 1987 were included in the survey. Among individuals with dysmorphic features or congenital anomalies 42% of babies referred in the neonatal period and 12 to 30% of individuals in older age
Cuschieri, Alfred, Gauci, Sandra
core  

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

open access: yesAdvanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong   +8 more
wiley   +1 more source

In silico analysis for the presence of HARDY an Arabidopsis drought tolerance DNA binding transcription factor product in chromosome 6 of Sorghum bicolor genome [PDF]

open access: yes, 2009
Expression of the Arabidopsis HARDY (hrd) DNA binding transcription factor (555 bp present on chromosome 2) has been shown to increase WUE in rice by Karaba et al 2007 (PNAS, 104:15270–15275). We conducted a detail analysis of the complete sorghum
Arun K. Shanker   +3 more
core   +2 more sources

Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality

open access: yesAdvanced Materials, EarlyView.
Harnessing and storing internally generated elastic energy is a clever strategy by biological materials to perform functions like shape transformation, movement, and predation. This review explores how biological systems manipulate mechanisms like atomic or protein integration into minerals, protein conformational shifts, phase transitions, and osmotic
Shahrouz Amini   +3 more
wiley   +1 more source

Energy Consumption Optimization in Trajectory Planning for Fuel Cell Hybrid Uavs Based On HMPC

open access: yesAdvanced Robotics Research, EarlyView.
The endurance limitation of multirotor drones is a critical challenge. This study adopts a hybrid power system of fuel cells and lithium‐ion batteries. Using Nondominated Sorting Genetic Algorithm II, it integrates trajectory planning with energy management optimization.
Xindi Wang   +7 more
wiley   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

open access: yesAdvanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

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