Results 181 to 190 of about 1,806,540 (343)
The accumulation of P-elements on the tip of theXchromosome in populations ofDrosophila melanogaster [PDF]
James W. Ajioka, Walter F. Eanes
openalex +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Diverse reference genomes detect variants in the US winter wheat. [PDF]
Parker K +7 more
europepmc +1 more source
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
SLiM 5: Eco-evolutionary Simulations Across Multiple Chromosomes and Full Genomes. [PDF]
Haller BC, Ralph PL, Messer PW.
europepmc +1 more source
Mobile messenger RNAs (mRNAs) can travel long distances, serving as systemic signals that participate in plant growth and stress acclimation. This work determines that PHR proteins mediate the Pi starvation response (PSR)‐specific long‐distance transport of mRNAs and that these PSR‐specific mobile mRNAs represent noncoding transcripts in recipient ...
Weiguo Dong +9 more
wiley +1 more source

