Results 211 to 220 of about 2,472,873 (391)

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

open access: yesAdvanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo   +6 more
wiley   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Publisher Correction: Functional interplay between condensin I and topoisomerase IIα in single-molecule DNA compaction

open access: yesNature Communications
Yuko Tsubota   +7 more
doaj   +1 more source

Publisher Correction: Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery

open access: yesScientific Reports, 2023
Kyotaro Yamazaki   +10 more
doaj   +1 more source

Developing Del2Phen: A Novel Phenotype Description Tool for Chromosome Deletions. [PDF]

open access: yesHum Mutat
Rraku E   +7 more
europepmc   +1 more source

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