Results 261 to 270 of about 1,806,540 (343)

Partial Monosomy 21q Due to De Novo t(15;21)(q26.3;q22.11): A Case Report with Clinical and Molecular Findings. [PDF]

Appl Clin Genet
Nojehdeh ST, Fattahi T, Arish S, Mokabber H, Nobakht R, Davarnia S, Davarnia B.   +6 more
europepmc   +1 more source

Chromosomal assignment of the gene for human elongation factor 2.

, 1984
Yasufumi Kaneda, Michihiro C. Yoshida, Kenji Kohno, Takafumi Uchida, Yasunori Okada   +4 more
openalex   +2 more sources

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

Where, When, and How? Integrating Spatiotemporal Cues in Cell Division. [PDF]

Bioessays
Cirillo L, Konthalapalli H, Alfieri C, Pines J.   +3 more
europepmc   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Surprisingly frequent chromosomal instability in cultivated peanut. [PDF]

Plant J
Lamon S, Abernathy BL, Leal-Bertioli SCM, Bertioli DJ.   +3 more
europepmc   +1 more source

Partial Tetrasomy of Chromosome 3q and Mosaicism in a Child with Autism

, 2003
Guiomar Oliveira, Eunice Matoso, Astrid M. Vicente, Patrícia Damasceno Ribeiro, Carla Marques, Assunção Ataíde, Teresa S. Miguel, Jorge Saraiva, Isabel M. Carreira   +8 more
openalex   +2 more sources

Chromosome Pairing [PDF]

Nature, 1973
openaire   +2 more sources

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Resolving interface structure and local internal mechanics of mitotic chromosomes. [PDF]

Nat Commun
Ridolfi A, Witt H, Harju J, Clement TVM, Peterman EEJG, Broedersz CP, Wuite GJL.   +6 more
europepmc   +1 more source