Results 321 to 330 of about 2,472,873 (391)

Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa

Advanced Science, EarlyView.
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong, Yanhong Liu, Yuanming Liu, Shuxin Xuan, Huanhuan Chen, Lai Wei, Guibao Zhang, Hongcui Pei, Zilong Dai, Yanhua Wang, Jinzhu Qiao, Shuangxia Luo, Xueping Chen, Yiguo Hong, Jianjun Zhao, Shuxing Shen, Zefu Lu, Aixia Gu   +17 more
wiley   +1 more source

False Positive or False Negative-An Interesting Case in Prenatal Diagnostic Laboratory. [PDF]

J Clin Lab Anal
Zhang P, Sun Y, Tian H, Shi X, Rong L, Li Y.   +5 more
europepmc   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Resolving interface structure and local internal mechanics of mitotic chromosomes. [PDF]

Nat Commun
Ridolfi A, Witt H, Harju J, Clement TVM, Peterman EEJG, Broedersz CP, Wuite GJL.   +6 more
europepmc   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Progress in Flax Genome Assembly from Nanopore Sequencing Data. [PDF]

Plants (Basel)
Pushkova EN, Arkhipov AA, Bolsheva NL, Rozhmina TA, Zhuchenko AA, Borkhert EV, Barsukov NM, Oleshnya GA, Milovanova AV, Moskalenko OD, Kostromskoy FD, Ivankina EA, Dvorianinova EM, Krupskaya DA, Melnikova NV, Dmitriev AA.   +15 more
europepmc   +1 more source

Evolution of chromosomes and nuclear architectures of amniotes. [PDF]

Nat Commun
Liu J, Zhou Q.
europepmc   +1 more source

Chromosomes of the succineid snail Catinella rotundata

, 2007
J. B. Burch
openalex   +1 more source

A Complex Chromosome Rearrangement Disrupting <i>SYT1</i> Supports Haploinsufficiency as a Cause of Baker-Gordon Syndrome. [PDF]

Case Rep Genet
Bertola DR, Farias SO, da Costa SS, Pinheiro MMLS, Passos-Bueno MRDS, Rosenberg C, Krepischi ACV.   +6 more
europepmc   +1 more source

Comparative Chromosomal Mapping of the 18S rDNA Loci in True Bugs: The First Data for 13 Genera of the Infraorders Cimicomorpha and Pentatomomorpha (Hemiptera, Heteroptera). [PDF]

Genes (Basel)
Golub NV, Anokhin BA, Grozeva S, Kuznetsova VG.   +3 more
europepmc   +1 more source