Results 331 to 340 of about 1,598,920 (365)

SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling

Advanced Science, EarlyView.
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou, Yang Gu, Zhibin Yi, Jianyi Wang, Zhen Xiong, Hui Guo, Ying Du, Xiaoxiao Zhu, Lei He, Weizheng Ren, Yong Tian, Yanying Wang, Zusen Fan   +12 more
wiley   +1 more source

Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis. [PDF]

Stem Cell Res Ther
Montilla-Rojo J, Hillenius S, Eleveld TF, Salvatori DCF, Looijenga LHJ.   +4 more
europepmc   +1 more source

Variant filters using segregation information improve mapping of nectar-production genes in sunflower (Helianthus annuus L.). [PDF]

Plant Genome
Barstow AC, McNellie JP, Smart BC, Keepers KG, Prasifka JR, Kane NC, Hulke BS.   +6 more
europepmc   +1 more source

The mechanism of tetraploidization in tree peony, and its implications for speciation and evolution of genus <i>Paeonia</i> L. [PDF]

Front Plant Sci
Zhong Y, Du MJ, Ji RZ, Cheng FY.
europepmc   +1 more source

Rapid evolution of a large highly-divergent haplotype region during a bacterial epidemic

Dexter E, Angst P, Fields P, Scheuber F, Henseler M, Ebert D.   +5 more
europepmc   +1 more source

Condensin I confers Stiffness and Centromeric Cohesion to Mitotic Chromosomes

Nielsen CF, Witt H, Ridolfi A, Kempers B, Chameau EM, van der Smagt S, Barisic M, Peterman EJ, Wuite GJ, Hickson ID.   +9 more
europepmc   +1 more source

Learning the dynamic organization of a replicating bacterial chromosome from time-course Hi-C data

Harju J, Messelink JJ, Tröger L, Gradziuk G, Rathnayaka I, Thanbichler M, van Teeseling MC, Broedersz CP.   +7 more
europepmc   +1 more source

Genome evolution in parthenogenetic nematodes shaped by chromosome rearrangements and rare sex

Chung G, Stevens L, Dai X, Hickey S, Kiontke K, Rughani P, Kieninger MR, Collins JC, Juul S, Piano F, Fitch DHA, Blaxter M, Gunsalus KC.   +12 more
europepmc   +1 more source

Chromosome imprinting and the mammalian X chromosome [PDF]

Nature, 1975
Chromosome imprinting is the process by which one of two genetically homologous chromosomes is predetermined to function differently from the other at a subsequent stage in development. In the coccid insects, imprinting occurs in the egg, at the time of fertilisation; it probably occurs at the same time and site in mammals, and possibly also in Sciara.
Spencer W. Brown, H. Sharat Chandra
openaire   +2 more sources

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Chromosomal Instability

Current Opinion in Oncology, 2004
This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
openaire   +2 more sources