Results 201 to 210 of about 769,627 (258)
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Mammalian Genome, 1997
Chromosome (Chr) 12 is a newcomer in the linkage genetics of the mouse. None of the classical linkage groups of the mouse map there, despite the suggested association of Va (LG XVI, now known to map to Chr 3) and the Chr 12 arm of the Rb(8.12)5Bnr Robertsonian chromosome (Cattanach and Moseley 1973). No genes were correctly assigned to Chr 12 until the
P, D'Eustachio, R, Riblet
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Chromosome (Chr) 12 is a newcomer in the linkage genetics of the mouse. None of the classical linkage groups of the mouse map there, despite the suggested association of Va (LG XVI, now known to map to Chr 3) and the Chr 12 arm of the Rb(8.12)5Bnr Robertsonian chromosome (Cattanach and Moseley 1973). No genes were correctly assigned to Chr 12 until the
P, D'Eustachio, R, Riblet
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American Journal of Medical Genetics, 1988
AbstractA ring chromosome 12 (p13.3q24.3) was observed in all cells analyzed from skin fibroblasts and the peripheral blood of a 19‐year‐old man initially referred for developmental delay with expressive language deficiency. Other phenotypic anomalies included growth deficiency, multiple café‐au‐lait spots, mild pectus excavatum, glandular hypospadias.
Jonathan P. Park +5 more
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AbstractA ring chromosome 12 (p13.3q24.3) was observed in all cells analyzed from skin fibroblasts and the peripheral blood of a 19‐year‐old man initially referred for developmental delay with expressive language deficiency. Other phenotypic anomalies included growth deficiency, multiple café‐au‐lait spots, mild pectus excavatum, glandular hypospadias.
Jonathan P. Park +5 more
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2023
Chromosome 12 spans about 134 million DNA building blocks and represents approximately 4.5 percent of the total cellular DNA. Gene dysregulation from chromosome 12 has triggered a cell to transform into a cancerous cell. Different types of genes are present in chromosome 12 that cause colon cancer, ovarian cancer, prostate cancer, ampulla of Vater ...
Yamini Chandraprakash +3 more
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Chromosome 12 spans about 134 million DNA building blocks and represents approximately 4.5 percent of the total cellular DNA. Gene dysregulation from chromosome 12 has triggered a cell to transform into a cancerous cell. Different types of genes are present in chromosome 12 that cause colon cancer, ovarian cancer, prostate cancer, ampulla of Vater ...
Yamini Chandraprakash +3 more
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The syndrome of ring chromosome 12
American Journal of Medical Genetics, 1980AbstractWe have studied a 13 month'old girl with failure to thrive, developmental delay, and dysmorphic features. At 13 months, the weight'age was 1 month, length'age was 3 months and head circumference was at the 3rd centile for 3 months. Physical findings were: Epicanthal folds, mildly cupped, apparently low'set ears, highly arched palate, short neck
Nina Scribanu +4 more
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Chromosomes 12 and 16 workshop
American Journal of Medical Genetics, 1999Recent linkage results independently derived from a large French Canadian pedigree and Danish kindreds coupled with supportive data from other studies provide compelling evidence for a bipolar disorder susceptibility locus on chromosome 12q23-q24. The idea is further strengthened by the finding that Darier's disease, which maps to this region, has been
Sevilla D. Detera‐Wadleigh +6 more
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Inversions of chromosome 12 in human malignancies
Cancer Genetics and Cytogenetics, 1987We present four cases with a malignant hematologic disorder and an inversion (peri- or paracentric) involving chromosome #12. Two cases of myelodysplastic syndrome showed an identical acquired pericentric inv(12)(p12q23). The pertinent literature on constitutional and acquired inversions of chromosome #12 has been revised.
I, Larripa +6 more
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A physical map of the chromosome 12 centromere
Cytogenetic and Genome Research, 2003While current sequencing efforts consider the detection of alpha satellite repeats as logical end points for map construction, detailed maps of most pericentromeric regions are lacking to confirm this hypothesis. Here we identify the different alpha satellite families present at the pericentromeric region of chromosome 12.
J R, Vermeesch +6 more
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Segmental tetrasomy of Chromosome 12 in the mouse
Cytogenetic and Genome Research, 1994An inbred strain of mice has been identified that is homozygous for a chromosomal segment attached to the centromeric region of Chromosome (Chr) 5. The altered chromosome arose spontaneously, and it does not appear to interfere with fertility or to have a phenotypic effect.
H, Katoh, M, Ebukuro, H, Suzuki
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