Establishing the Link between X-Chromosome Aberrations and TP53 Status, with Breast Cancer Patient Outcomes. [PDF]
Cells, 2023 Caramia F +4 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
The Relationship between Screening Markers in the First Trimester of Pregnancy and Chromosome Aberrations. [PDF]
Int J Prev Med, 2022 Mirsafaie M +2 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Summary of chromosome 11 aberrations. [PDF]
, 2013 Large chromosomal aberrations are indicated with colored bars around the ideogram of chromosome 11. Green – gains; red – deletions; blue – uniparental disomies.
Bettina Gisslinger (471226) +27 more
core +1 more source
Фактори експериментальної еволюції організмів, 2016 Aim. Investigation the influence of astaxanthin on the radiation-induced cytogenetic effect in human peripheral blood lymphocytes. Methods. Astaxanthin in optimal concentration (20.0 μg/ml), established in the previous own research, added to culture of ...
Д. А. Курінний
doaj
Background Level of Unstable Chromosome Aberrations in the Kazakhstan Population: A Human Biomonitoring Study. [PDF]
Int J Environ Res Public Health, 2022 Kenzhina LB +10 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Semen quality in men with Y chromosome aberrations [PDF]
, 2010 Infertile males sometimes bear structurally balanced chromosome aberrations, such as translocations and inversions, which involve both autosomes and sex chromosomes.
MARCUCCI, LIANA +16 more
core +1 more source
A cloud-based resource for genome coordinate-based exploration and large-scale analysis of chromosome aberrations and gene fusions in cancer. [PDF]
Genes Chromosomes Cancer, 2023 Wang J +12 more
europepmc +1 more source