Results 171 to 180 of about 126,155 (293)

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

Advanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang, Rui Yan, Jing Guo, Mengyao Wang, Xin Cheng, Fan Zhang, Tianzi Guo, Xin Long, Fan Guo, Dan Liang   +9 more
wiley   +1 more source

Cytogenetic profile in patients with primary myelodysplastic syndrome

Терапевтический архив, 2013
AIM: To analyze the prevalence of chromosome aberrations presented in the revised International Prognostic Scoring System (R-IPSS) in patients with de novo myelodysplastic syndrome (MDS)/MATERIAL AND METHODS: Chromosome aberrations were analyzed in 197 ...
S V Gritsaev, I S Martynkevich, E V Petrova, L S Martynenko, M P Ivanova, V Iu Aksenova, N Iu Tsybakova, N A Potikhonova, K M Abdulkadyrov   +8 more
doaj  

Using three-color chromosome painting to test chromosome aberration models.

, 1993
J. N. Lucas, Allen Chen
openalex   +2 more sources

Prevalence of chromosomal aberrations in breeding pigs in Spain [PDF]

, 2019
Raúl Sánchez Sánchez, Ernesto Gómez‐Fidalgo, Sonia S. Pérez‐Garnelo, M. Martín Lluch, Paloma De la Cruz‐Vigo   +4 more
openalex   +1 more source

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

Advanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani, Eric Reed, Kevin B Chandler, Prisma Lopez, Hannah Lords, Harold Bae, Catherine E Costello, Matthew Au, Lingyi Lynn Deng, Mengze Li, Qingyan Xiang, Heeju Noh, Lance Pflieger, Cory Funk, Noa Rappaport, Marianne Nygaard, Meghan I Short, Michael Brent, Stefano Monti, Stacy L Andersen, Thomas T Perls   +20 more
wiley   +1 more source

Simultaneous Exposure of Cultured Human Lymphoblastic Cells to Simulated Microgravity and Radiation Increases Chromosome Aberrations. [PDF]

Life (Basel), 2020
Yamanouchi S, Rhone J, Mao JH, Fujiwara K, Saganti PB, Takahashi A, Hada M.   +6 more
europepmc   +1 more source

Detection of genetic imbalances in tumor genomes by fluorescence in situ hybridization with tumor genomic DNA and subregional DNA probes [PDF]

, 1993
Cremer, Thomas, Jauch, Anna, Joos, Stefan, Lengauer, Christoph, Lichter, Peter, Manoir, Stanislas du, Natarajan, Adayapalam T., Obe, Günter, Popp, Susanne, Ried, Thomas, Scherthan, Harry, Schröck, Evelin, Speicher, Michael R.   +12 more
core   +1 more source

Suppressing Effects of Flavorings on the Induction of Gene Mutations and Chromosome Aberrations.

, 1993
Toshihiro Ohta
openalex   +2 more sources

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

Chromosomal aberrations in hepatocellular carcinomas: Relationship with pathological features [PDF]

, 1997
U. Zimmermann
openalex   +1 more source