Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng +15 more
wiley +1 more source
Rapid and High-Throughput Detection of Peripheral Blood Chromosome Aberrations in Radiation Workers. [PDF]
Bi J +7 more
europepmc +1 more source
THE INDUCTION OF CHROMOSOMAL ABERRATIONS IN VITRO BY ALLOGENEIC LYMPHOCYTE EXTRACT
Philip J. Fialkow
openalex +1 more source
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou +30 more
wiley +1 more source
A Bi-Exponential Repair Algorithm for Radiation-Induced Double-Strand Breaks: Application to Simulation of Chromosome Aberrations. [PDF]
Plante I, Slaba T, Shavers Z, Hada M.
europepmc +1 more source
RECENT STUDIES ON CHROMOSOME ABERRATIONS INDUCED BY VIRUSES
Kazuhiko R. Utsumi
openalex +2 more sources
Dose-response Relationship of Lymphocyte Chromosome Aberrations in Locally Irradiated Persons [PDF]
Sho Matsubara +2 more
openalex +1 more source
Engineering Bacteria as Living Therapeutics in Cancer Therapy
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen +6 more
wiley +1 more source
Production and distribution of chromosome aberrations in human lymphocytes by particle beams with different LET. [PDF]
Kowalska A +5 more
europepmc +1 more source

