Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge+7 more
wiley +1 more source
Rapid and High-Throughput Detection of Peripheral Blood Chromosome Aberrations in Radiation Workers. [PDF]
Bi J+7 more
europepmc +1 more source
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu+11 more
wiley +1 more source
A Bi-Exponential Repair Algorithm for Radiation-Induced Double-Strand Breaks: Application to Simulation of Chromosome Aberrations. [PDF]
Plante I, Slaba T, Shavers Z, Hada M.
europepmc +1 more source
Effects of 2.4-dinitrophenol on the frequencies of X-ray induced chromosome aberrations in barley.
lCHIZO NISHIYAMA, Noriko Ohta
openalex +2 more sources
Relationship Between the Radiation Dose and Chromosome Aberrations in Atomic Bomb Survivors of Hiroshima and Nagasaki [PDF]
A A Awa+5 more
openalex +1 more source
Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu+9 more
wiley +1 more source
Production and distribution of chromosome aberrations in human lymphocytes by particle beams with different LET. [PDF]
Kowalska A+5 more
europepmc +1 more source
THE INDUCTION OF CHROMOSOMAL ABERRATIONS IN VITRO BY ALLOGENEIC LYMPHOCYTE EXTRACT
Philip J. Fialkow
openalex +1 more source