Results 171 to 180 of about 55,436 (218)

Beyond Structure: Methylation Fine‐Tunes Stability and Folding Kinetics of bcl2Mid G‐Quadruplex

Angewandte Chemie, EarlyView.
The introduction of a single 5‐methylcytosine into a G‐rich sequence originating from the B‐cell lymphoma 2 (BCL2) gene promoter affects both the folding kinetics and thermodynamics of the two G4 structures and thus plays a crucial role in regulating G4 folding pathways, which has significant implications for the control of gene expression.
Nataša Medved, Mirko Cevec, Uroš Javornik, Jurij Lah, San Hadži, Janez Plavec   +5 more
wiley   +2 more sources

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Genetic and environmental associations of nonspecific chromosomal aberrations. [PDF]

Mutagenesis
Hemminki K, Niazi Y, Vodickova L, Vodicka P, Försti A.   +4 more
europepmc   +1 more source

A Mosaic Hotspot PLCD1 Variant, Detectable in Blood‐Derived DNA, Associated With Nevus Trichilemmocysticus

American Journal of Medical Genetics Part A, EarlyView.
Leanne de Kock, Macarena Nougues, Madeline Couse, Wendy Mears, Alison J. Eaton, Kristin D. Kernohan, Care4Rare Canada Consortium, Margarita Larralde, Kym M. Boycott   +8 more
wiley   +1 more source

Evaluation of Clastogenic and Aneugenic Action of Two Bio-Insecticides Using Allium Bioassay. [PDF]

J Xenobiot
Duta-Cornescu G, Dugala ML, Constantin N, Pojoga MD, Simon-Gruita A.   +4 more
europepmc   +1 more source

Clinical Value of MLPA for Prognostic Assessment of Chromosomal Rearrangements and DNA Methylation in Uveal Melanoma. [PDF]

Invest Ophthalmol Vis Sci
Soltysova A, Dvorska D, Ficek A, Pecimonova M, Samec M, Kasubova I, Horvathova Kajabova V, Demkova L, Babal P, Valaskova J, Dankova Z, Smolkova B, Furdova A.   +12 more
europepmc   +1 more source

Assessment of the predictive power the radiation-induced lymphocyte apoptosis method in prostate cancer patients. [PDF]

Sci Rep
Sándor GO, Farkas G, Székely G, Ágoston P, Jorgo K, Gesztesi L, Major T, Pesznyák C, Herein A, Stelczer G, Mihály D, Fröhlich G, Jurányi Z, Takácsi-Nagy Z, Polgár C, Kocsis ZS.   +15 more
europepmc   +1 more source

An Incidental Finding of Gain of a Diminished Chromosome 12 Centromere in an Individual with Lymphocytosis: A Case Report and Clinical Implications in Cytogenetic Testing. [PDF]

Diagnostics (Basel)
Xia C, Cannatella JJ, Smith SC, Althof PA, Koerselman H, Hempel T, Jaworski EE, Winkler LM, Spaulding JR, Pickering D, Khoury JD, Tang Z.   +11 more
europepmc   +1 more source

Genotoxic effects of NDMA-contaminated ranitidine on Allium cepa cells and unveiling carcinogenic mechanisms via DFT and molecular dynamics simulation study. [PDF]

Sci Rep
Kaly MK, Rahman ME, Rana MS, Acharjee UK, Nasirujjaman K.   +4 more
europepmc   +1 more source

Identification of genomic biomarkers of disease progression and survival in primary CNS lymphoma. [PDF]

Blood Adv
Geng H, Mo S, Chen L, Ballapuram A, Tsang M, Lu M, Rauschecker AM, Wen KW, Devine WP, Solomon DA, Rubenstein JL.   +10 more
europepmc   +1 more source