Results 181 to 190 of about 55,436 (218)
Heterochromatin and chromosome aberrations [PDF]
Chromosoma, 1969 The chromosome breaking effect of mitomycin C, methyl methanesulfonate, maleic hydrazide, 8-ethoxycaffeine and gamma rays on the primary root meristematic cells of Nigella damascena was studied. All the agents tested except 8-ethoxycaffeine, produced relatively fewer aberrations, when compared to Vicia faba cells, though both the species have nearly ...
A. T. Natarajan, G. Ahnström
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Chromosome Aberrations and Cancer
Science, 1991Cancer may be defined as a progressive series of genetic events that occur in a single clone of cells because of alterations in a limited number of specific genes: the oncogenes and tumor suppressor genes. The association of consistent chromosome aberrations with particular types of cancer has led to the identification of some of these genes and the ...
Audrey Goddard +2 more
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The fate of chromosome aberrations
Journal of Theoretical Biology, 1973Abstract Chromosomal aberrations rapidly disappear from populations of dividing cells, but little is known about the details of the process. One may ask, for example, whether a cell with an acentric fragment is virtually certain to die after the first mitosis or whether it has a high probability of surviving to the second.
Anthony V. Carrano, John A. Heddle
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Chromosomal aberrations in man
The Journal of Pediatrics, 1961Summary The following are the most significant points to emerge in summarizing the present status of the field of human cytogenetics. 1. The human chromosome number is 46; a standard system of nomenclature has been established for identification of somatic metaphase chromosomes.
Stanley Rappoport, William D. Kaplan
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On the formation of chromosomal aberrations
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1970Abstract The exchange hypothesis and the breakage-first hypothesis are the 2 major hypotheses that describe how chromosomal aberrations might be produced. A critical test has shown that one important aspect of the exchange hypothesis is correct, namely that some aberrations that appear to be simple chromatid deletions are actually incomplete ...
D. J. Bodycote, John A. Heddle
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ULTRASOUND AND CHROMOSOME ABERRATIONS
Medical Journal of Australia, 1973Human and marsupial whole blood and blood-medium mixtures were irradiated with various doses of 2.25 MHz ultrasound and gamma rays. Doses of ultrasonic irradiation orders of magnitude higher than those used for diagnostic studies produced very few chromosome aberrations.
Geard Cr +4 more
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Chromosomal aberrations in malnutrition
Metabolism, 1975The effects of feeding high (18%) and low (5%) protein diets on chromosomal aberrations in bone marrow cells of rats were investigated. Malnourished rats maintained on low protein diet had significantly higher incidence of breaks and deletions as compared to wellfed rats maintained on high protein diet. Well fed rats showed an increased aberration rate
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Chromosome Structural Aberrations
1980Structural chromosome abnormalities are relatively frequent in human populations. They are the result of breaks that disrupt the continuity of one or more chromosomes. Chromosome breaks in the germline can lead to heritable structural abnormalities; those occurring in somatic cells may increase the risk of cancer.
Orlando J. Miller, Eeva Therman
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Autosomal Chromosome Aberrations
1976Prior to the introduction of cytogenetic techniques in human medicine some 15 years ago, only a single chromosome aberration syndrome, Down’s syndrome, was known clinically, but its etiology was still unclear. By direct chromosome examination, it was later shown that the clinical picture of Down’s syndrome is caused by the presence of an additional No.
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Food Additives & Contaminants, 1984
Three points related to the subject of chromosome-aberration tests and carcinogenicity screening are dealt with in this paper. First, the relation between chromosome rearrangements and oncogenesis is briefly discussed, to stress the relevance of cytogenetic assays to assessment of the carcinogenic potential of drugs.
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Three points related to the subject of chromosome-aberration tests and carcinogenicity screening are dealt with in this paper. First, the relation between chromosome rearrangements and oncogenesis is briefly discussed, to stress the relevance of cytogenetic assays to assessment of the carcinogenic potential of drugs.
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