A Study on Time- and Radiation-dependent Changes in the Frequency of Lymphocytes with Chromosome Aberrations in the Circulation, Following Multiple Exposures of the Pelvis to γ-Irradiation [PDF]
, 1970 Hiroaki Tamura +2 more
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Advanced Science, EarlyView.This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li +6 more
wiley +1 more source
Letter to the Editor on "Chrysotile and rock wool fibers induce chromosome aberrations and DNA damage in V79 lung fibroblast cells". [PDF]
Environ Sci Pollut Res Int, 2019 Hadley JG, Crane AE.
europepmc +1 more source
Chromosome aberrations of cultured human leukocytes induced by metabolites of benzene
, 1968 Minoru Takata, Akio Koizumi
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Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica
Advanced Science, EarlyView.The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon +8 more
wiley +1 more source
Advanced Science, EarlyView.Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li +6 more
wiley +1 more source
Straightening Beta: Overdispersion of Lethal Chromosome Aberrations following Radiotherapeutic Doses Leads to Terminal Linearity in the Alpha-Beta Model. [PDF]
Front Oncol, 2017 Shuryak I, Loucas BD, Cornforth MN.
europepmc +1 more source
Chromosome Aberrations in Workers Exposed to Arsenic
, 1977 G. Beckman, L. Beckman, Ingrid Nordenson
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Advanced Science, EarlyView.Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan +10 more
wiley +1 more source
Enlarged NT (≥3.5 mm) in the first trimester - not all chromosome aberrations can be detected by NIPT. [PDF]
Mol Cytogenet, 2016 Srebniak MI +11 more
europepmc +1 more source