Results 151 to 160 of about 379,249 (335)

Supplementary Material for: Optical genome mapping for a patient with a congenital disorder and chromosomal translocation

, 2023
Damin Asadov, Gloria S. Huang, Mirzagolib Tillashaykhov, Xie Ge, Katie Tayler‐Smith, John d a c- f - f c-a - b ffa d dc, Robert S. Fujinami   +6 more
openalex   +1 more source

Effectiveness of the preventive intervention of chromosomal disorders of Iran's community genetics program: Application of bayesian network [PDF]

, 2021
Seyyedeh Sara Azimi, Sama Ashraf Samavat, Vahid Rezaei Tabar, Hamid Soori   +3 more
openalex   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Linkage to Chromosome 1p36 for Attention-Deficit/Hyperactivity Disorder Traits in School and Home Settings

, 2008
Kaixin Zhou, Philip Asherson, Pak C. Sham, Barbara Franke, Richard Anney, Jan K. Buitelaar, Richard P. Ebstein, Michael Gill, Keeley J. Brookes, Cathelijne J.M. Buschgens, Desmond Campbell, Wai Chen, Hanna Christiansen, Ellen A. Fliers, Isabel Gabriëls, Lena Johansson, Rafaela Marco, Fernando Mulas, Ueli C. Müller, Aisling Mulligan, Benjamin M. Neale, Frühling Rijsdijk, Nanda Rommelse, Henrik Uebel, Lamprini Psychogiou, Xiaohui Xu, Tobias Banaschewski, Edmund Sonuga‐Barke, Jacques Eisenberg, Iris Manor, Ana Miranda, Robert D. Oades, Herbert Roeyers, Aribert Rothenberger, Joseph A. Sergeant, Hans‐Christoph Steinhausen, Eric Taylor, Margaret Thompson, Stephen V. Faraone   +38 more
openalex   +2 more sources

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

Psychotic disorder and its characteristics in sex chromosome aneuploidies

, 2009
Annapia Verri, Anna Cremante
openalex   +2 more sources

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

Identification of a Chromosome 11q23.2-q24 Locus for Familial Aortic Aneurysm Disease, a Genetically Heterogeneous Disorder [PDF]

, 2001
Carl J. Vaughan, Mairead Casey, Jié He, Mark Veugelers, Kiersten A. Henderson, Dongchuan Guo, R.J. Campagna, Mary J. Roman, Dianna M. Milewicz, Richard B. Devereux, Craig T. Basson   +10 more
openalex   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source