Results 161 to 170 of about 3,786,126 (364)
Advanced Science, EarlyView.Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho +12 more
wiley +1 more source
Advanced Science, EarlyView.MRC is a live‐cell method enabling visualization of protein–protein interactions and biomolecular condensates. It supports multi‐protein colocalization, binding analysis, and programmable condensate manipulation, providing a versatile platform for studying dynamic cellular organization.
Lei Peng +8 more
wiley +1 more source
Frequency of Chromosome Disorders In Patients with Sperm Number Anomaly
Gazi Medical JournalObjective: Chromosome abnormalities play an important role in male infertility. The rate of chromosome disorders in infertile men is higher as 5.8% when compared to the normal population (0.5%).
Mehmet Niyaz +2 more
doaj +1 more source
Fibrodysplasia Ossificans Progressiva, a Heritable Disorder of Severe Heterotopic Ossification, Maps to Human Chromosome 4q27-31* [PDF]
, 2000 George Feldman +12 more
openalex +1 more source
Advanced Science, EarlyView.Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge +7 more
wiley +1 more source
Human male infertility: chromosome anomalies, meiotic disorders, abnormal spermatozoa and recurrent abortion [PDF]
, 2000 Susana Egozcue
openalex +1 more source
Book Review: The Chromosome Disorders [PDF]
Proceedings of the Royal Society of Medicine, 1966 openaire +3 more sources
Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury
Advanced Science, EarlyView.This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong +10 more
wiley +1 more source
Advanced Science, EarlyView.Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li +6 more
wiley +1 more source