Results 191 to 200 of about 3,861,183 (367)

A major role for common genetic variation in anxiety disorders

Molecular Psychiatry, 2019
K. Purves, J. Coleman, S. Meier, C. Rayner, K. Davis, R. Cheesman, Marie Bækvad-Hansen, A. Børglum, Shing Wan Cho, J. Deckert, Héléna A. Gaspar, J. Bybjerg-Grauholm, J. Hettema, M. Hotopf, D. Hougaard, Christopher Hübel, C. Kan, A. McIntosh, O. Mors, P. Mortensen, M. Nordentoft, T. Werge, K. Nicodemus, M. Mattheisen, G. Breen, T. Eley   +25 more
semanticscholar   +1 more source

ACE‐mediated Glycosylation Stabilizes PSAP To Promote GPR37‐dependent Macrophage‐Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo, Feng Wang, Bijun Wang, Yu Zhou, Chao Wang, Tao Hu, Desheng Wu   +6 more
wiley   +1 more source

Clinical and Molecular Presentation of a Patient with Paternal Uniparental Isodisomy of Chromosome 16. [PDF]

Int J Mol Sci
Panchenko E, Semenova N, Sereda O, Guseva D, Markova Z, Shilova N, Simonova O, Smirnov A, Pustoshilov D, Khalilova A, Udalova V, Kanivets I, Zaletaev D, Strelnikov V, Kutsev S.   +14 more
europepmc   +1 more source

The Novel Genetic Disorder Microhydranencephaly Maps to Chromosome 16p13.3-12.1

, 2000
G. N. KAVASLAR, Suna Önengüt, Orhan Derman, A. Kaya, Aslıhan Tolun   +4 more
openalex   +1 more source

Phenotypic Homogeneity Provides Increased Support for Linkage on Chromosome 2 in Autistic Disorder [PDF]

, 2002
Yujun Shao, Kimberly L. Raiford, Chantelle M. Wolpert, Heidi Cope, Sarah A. Ravan, Allison E. Ashley‐Koch, Ruth K. Abramson, Harry H. Wright, Robert DeLong, John R. Gilbert, Michael L. Cuccaro, Margaret A. Pericak‐Vance   +11 more
openalex   +1 more source

The Chromosome Disorders

, 1970
S. Walters, N. Gregersen
semanticscholar   +1 more source

Chromosome conformation elucidates regulatory relationships in developing human brain

Nature, 2016
H. Won, L. Torre-Ubieta, J. Stein, N. Parikshak, Jerry Huang, Carli K. Opland, M. Gandal, G. J. Sutton, F. Hormozdiari, D. Lu, Changhoon Lee, E. Eskin, I. Voineagu, J. Ernst, D. Geschwind   +14 more
semanticscholar   +1 more source

Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex

Advanced Science, EarlyView.
The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua, Xuyang Ding, Yanan Wu, Di Zhang, Xinlin Hu, Ping Yang, Jiameng Li, Yi Tan, Junbo Liu, Mingjie Zhang, Min Zhang, Xiaotian Liu, Hongjun Yu   +12 more
wiley   +1 more source

A Novel Homozygous GFI1B Mutation in Siblings With Thrombocytopenia and Bleeding Tendency. [PDF]

Clin Case Rep
Aryal S, Aryal S, Adhikari S, Adhikari P.   +3 more
europepmc   +1 more source

A Case of Phenylketonuria with Chromosomal Disorder

, 1969
Bahtiyar Demirağ
openalex   +1 more source