Results 201 to 210 of about 217,829 (265)

Contrasting the genetic architecture of cardiac glutathione against other organs: unveiling a unique tissue-specific locus. [PDF]

Mamm Genome
Strosahl J, McClatchy S, Churchill GA, Koch RL, Craig SW, Pazdro R.   +5 more
europepmc   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

De Novo Complex Genomic Rearrangement Spanning 2q31.1 in a Proband With Congenital Malformations: Genotype-Phenotype Correlation and Development of a CGR Detection Pipeline. [PDF]

Am J Med Genet A
Helle K, Bengtsson JD, Gandhi M, Grochowski CM, Lun MY, Sudhir N, Jhangiani SN, Sedlazeck FJ, Lalani SR, Hanchard NA, Carvalho CMB.   +10 more
europepmc   +1 more source

Genetic dissection and transcriptomic analysis of a novel high-tillering phenotype in rice derived from weedy rice (Hapcheonaengmi3) and Tongil-type Rice (Milyang23). [PDF]

Plant Genome
Shim KC, Jeon D, Jeon YA, Adeva C, Lee HS, Kang JW, Park SE, Ahn SN, Park I.   +8 more
europepmc   +1 more source

An improved Solanum verrucosum genome provides insight into potato centromeres and epigenetic regulation. [PDF]

G3 (Bethesda)
Smith M, Kaur A, Singh V, Jones JT, Hein I.   +4 more
europepmc   +1 more source

Telomere-to-telomere characterization of rDNA chromosome in the myxomycete Didymium iridis. [PDF]

BMC Mol Cell Biol
Khan A, Jørgensen TE, Jakt LM, Karlsen BO, Hedberg A, Johansen SD.   +5 more
europepmc   +1 more source

A high-density SNP linkage map reveals a major LG3 QTL hotspot controlling early-maturity-related traits in ridge gourd (<i>Luffa acutangula</i>). [PDF]

Front Plant Sci
Chen Q, Guo Y, Li Y, Zhang L, Song H, Zeng Z, Su G, Deng J, Sun X, He X, Kang D, Chen Z.   +11 more
europepmc   +1 more source

Genetic architecture of angular leaf spot resistance in cultivated strawberry shaped by epistasis and genotype-by-environment interactions. [PDF]

Plant Genome
Torgeman S, Pincot DDA, Bjornson M, Famula RA, Skillin P, Krill-Brown A, Feldmann MJ.   +6 more
europepmc   +1 more source

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Mapping human chromosomes

Current Opinion in Genetics & Development, 1995
The construction of integrated maps at all levels of resolution will facilitate determination of the DNA sequence and, ultimately, the entire gene content of the human genome. In the past two years, the need for extensive frameworks on which to anchor the maps of the human chromosomes has been emphasized. The first framework has been provided following
D R, Bently, I, Dunham
openaire   +2 more sources

Mapping the Phytoplasma Chromosome

2012
Physical and genetic mapping of the phytoplasma chromosome can be a useful tool in a genome sequencing project in order to assemble the in silico-predicted contigs robustly. Mapping consists of four distinct steps: preparation of phytoplasma chromosomes from infected plants, single- and double-digestion of chromosomes with rare-cutting restriction ...
Malembic-Maher, Sylvie, Carle, Patricia
openaire   +4 more sources