Results 231 to 240 of about 2,127,240 (398)

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

open access: yesAdvanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou   +8 more
wiley   +1 more source

Isolation and mapping of a polymorphic DNA sequence (pMHZ17) on chromosome 13 [D13S51] [PDF]

open access: green, 1988
M. Hoff   +7 more
openalex   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

open access: yesAdvanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria   +5 more
wiley   +1 more source

SENP6 Maintains Mitochondrial Homeostasis by Regulating Mitochondrial Protein Import Through deSUMOylation of TOM40

open access: yesAdvanced Science, EarlyView.
SUMOylation regulates mitochondrial processes, but its impact on protein import remains unclear. TOM40 is identified, a mitochondrial outer membrane channel protein, as a substrate of deSUMOylase SENP6. TOM40 SUMOylation disrupts outer membrane complex assembly, inhibits protein import, and compromises mitochondrial homeostasis.
Liubing Hu   +13 more
wiley   +1 more source

Chromosome-level assembly of the 400-year-old Goethe's Palm (Chamaerops humilis L.). [PDF]

open access: yesSci Data
Beltran-Sanz N   +7 more
europepmc   +1 more source

Isolation and mapping of a polymorphic DNA sequence (CJ52.112) on chromosome 16 [D16S158] [PDF]

open access: bronze, 1989
Cécile Julier   +4 more
openalex   +1 more source

Chromosome Mapping in Staphylococcus aureus

open access: yesJournal of Bacteriology, 1968
R. Altenbern
semanticscholar   +1 more source

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