Results 71 to 80 of about 217,829 (265)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Advanced ScienceComparative fluorescence in situ hybridization (FISH) mapping, particularly chromosome painting, was first developed in mammalian systems and generated much of the foundational knowledge on chromosomal relationships among diverse mammalian species prior ...
Li He +9 more
doaj +1 more source
Karyological analysis of Acanthocephalus ranae (Echinorhynchida): expanding the cytogenetic knowledge in acanthocephalans [PDF]
ZooKeysThis study presents the first comprehensive cytogenetic analysis of the common amphibian parasite Acanthocephalus ranae. A combination of classical cytogenetic methods and molecular techniques, including the fluorescence in situ hybridization (FISH ...
Martina Orosová, Anna Marková
doaj +3 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
BMC Genomics, 2018 Background Malaria mosquitoes have had a remarkable stability in the number of chromosomes in their karyotype (2n = 6) during 100 million years of evolution.
Gleb N. Artemov +5 more
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FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Chromosome Segmentation and Investigations using Generalized Gradient Vector Flow Active Contours
Online Journal of Health & Allied Sciences, 2005 We investigated Generalized Gradient Vector Flow Active Contours as a suitable boundary mapping technique for Chromosome spread images which have variability in shape and size, expecting to yield a robust segmentation scheme that can be used for ...
Albert Prabhu Britto +1 more
doaj
Current Plant Biology, 2019 Sorghum downy mildew (SDM) caused by the Oomycete, Peronosclerospora sorghi ((Weston and Uppal) C. G. Shaw) is a major impediment to maize production and productivity.
K.P. Jadhav +6 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source