Results 71 to 80 of about 1,677,599 (311)

Early events in the evolution of the Silene latifolia Y chromosome: Male specialization and recombination arrest [PDF]

, 2007
Understanding the origin and evolution of sex chromosomes requires studying recently evolved X-Y chromosome systems such as those in some flowering plants.
Georgiev, Sevdalin, Zluvova, Jitka, Janousek, Bohuslav, Georgiev, S., Vyskot, Boris, Negrutiu, Loan, Negrutiu, Ioan, Charlesworth, D., Charlesworth, Deborah   +8 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

2: The Mapping of Chromosome 16 [PDF]

, 1992
Human chromosome 16 is the main focus of the mapping efforts at Los Alamos. The large photomicrograph on these opening pages illustrates the starting point for those mapping efforts, the evaluation of our chromosome-16-specific library of cloned ...
Doggett, Norman A., Hildebrand, Carl E., Stallings, Raymond L., Moyzis, Robert K.   +3 more
core  

GENETICS AND GENOMICS OF PLANT GENETIC RESOURCES [PDF]

Journal of Stress Physiology & Biochemistry, 2012
Plant genetic resources play a major role for global food security. The most significant and widespread mean of conserving plant genetic resources is ex situ conservation.
Börner A., E.K. Khlestkina, T.A. Pshenichnikova, S.V. Osipova, B. Kobiljski, S. Landjeva, M.R. Simon, M. Nagel, M.A. Rehman Arif, K. Neumann, U. Lohwasser, M.S. Röder   +11 more
doaj  

Common Wheat Chromosome 5B Composition Analysis Using Low-Coverage 454 Sequencing

The Plant Genome, 2014
The sequencing of individual chromosomes of common wheat is in progress. The molecular size of wheat chromosome 5B is nearly 870 Mb (5BL = 580 Mb and 5BS = 290 Mb).
E. M. Sergeeva, D. A. Afonnikov, M. K. Koltunova, V. D. Gusev, L. A. Miroshnichenko, J. Vrána, M. Kubaláková, C. Poncet, P. Sourdille, C. Feuillet, J. Doležel, E. A. Salina   +11 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Chromosome drives via CRISPR-Cas9 in yeast

Nature Communications, 2020
Self-propagating drive systems are capable of causing non-Mendelian inheritance. Here, we report a drive system in yeast referred to as a chromosome drive that eliminates the target chromosome via CRISPR-Cas9, enabling the transmission of the desired ...
Hui Xu, Mingzhe Han, Shiyi Zhou, Bing-Zhi Li, Yi Wu, Ying-Jin Yuan   +5 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm. [PDF]

, 2005
BACKGROUND The male-specific region of the mouse Y chromosome long arm (MSYq) is comprised largely of repeated DNA, including multiple copies of the spermatid-expressed Ssty gene family.
Ojarikre, Obah A., Obah A Ojarikre, Clemente, Emily J., Reynard, Louise, Affara, Nabeel A., Peter Ellis, Mahadevaiah, Shantha K., Ellis, Peter J.I., Ball, Penny A.F., Peter JI Ellis, Shantha K Mahadevaiah, Nabeel A Affara, Loveland, Kate L., Burgoyne, Paul S., Louise Reynard, Kate L Loveland, Aminata Touré, Touré, Aminata, Emily J Clemente, Penny AF Ball, Paul S Burgoyne   +20 more
core   +7 more sources

Quantitative Genetic Mapping and Genome Assembly in the Lesser Wax Moth Achroia grisella

G3: Genes, Genomes, Genetics, 2019
Specific characteristics of the male Achroia grisella acoustic mating signal determine a male’s attractiveness toward females. These features are genetically variable in populations, and mapping experiments have been used to identify loci contributing to
Boryana S. Koseva, Jennifer L. Hackett, Yihong Zhou, Bethany R. Harris, John K. Kelly, Michael D. Greenfield, Jennifer M. Gleason, Stuart J. Macdonald   +7 more
doaj   +1 more source