Results 221 to 230 of about 821,591 (309)
Unveiling Multi‐Scale Architectural Features in Single‐Cell Hi‐C Data Using scCAFE
scCAFE is a deep learning framework designed to identify multi‐scale 3D genome architectural features from single‐cell Hi‐C data without dense imputation. It predicts chromatin loops, TAD‐like domains, and A/B compartments, enabling efficient characterization of organization at the single‐cell level. scCAFE also identifies marker loop anchors, offering
Fuzhou Wang+12 more
wiley +1 more source
THE LOWEST CHROMOSOME NUMBER IN COLEOPTERA
Niilo Virkki, Caridad M. Purcell
openalex +2 more sources
Cytogenetic Studies inPapaverII. Hybrids Among Species with 7 as the Haploid Chromosome Number [PDF]
C. P. Malik, I. S. Grover
openalex +1 more source
This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu+19 more
wiley +1 more source
Variation in Chromosome Number and its role in Speciation inDracaena MetallicaHort. [PDF]
Piyali Datta
openalex +1 more source
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu+12 more
wiley +1 more source
This study presents an innovative method to generate high‐quality, objectively annotated cytology datasets without relying on expert involvement. Large‐scale single‐cell DNA sequencing is used as an objective ground truth of cell annotation for generating an accurate, unbiased dataset of exfoliated tumor cells from bronchoalveolar lavage cytology ...
Yichun Zhao+10 more
wiley +1 more source
Chromosome Number and Morphology in Nicotiana VI [PDF]
openaire +3 more sources
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi+8 more
wiley +1 more source