Results 281 to 290 of about 803,632 (356)

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

open access: yesAdvanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li   +9 more
wiley   +1 more source
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The chromosome number in man

The Indian Journal of Pediatrics, 1963
The chromosome number has been determined in an Indian female adult, the first to be reported in this ethnic group. The chromosome studies were made on leucocytes obtained from the short-term culture of peripheral blood.
A, CHAUDHURI, K C, CHAUDHURI
openaire   +2 more sources

Inferring hypothesis-based transitions in clade-specific models of chromosome number evolution in sedges (Cyperaceae).

Molecular Phylogenetics and Evolution, 2019
Large-scale changes in chromosome number have been associated with diversification rate shifts in many lineages of plants. For instance, several ancient rounds of polyploidization events have been inferred to promote genomic differentiation and/or ...
J. I. Márquez‐Corro   +4 more
semanticscholar   +1 more source

Chromosome Numbers of Slugs

Nature, 1960
CHROMOSOME numbers are becoming increasingly part of the taxonomic descriptions of animal and plant species.
openaire   +2 more sources

Chromosome number 18

Human Genetics, 1973
4 cases of “? chromosome abnormality”, referred to this department in the past 3 months, have shown an aberrant complement of chromosome 18. Chromosome 18 has been identified using a modification of Seabright's (1971) method of banding human chromosomes.
openaire   +2 more sources

Chromosome numbers inCrocus

Genetica, 1959
1. SevenCrocus species collected in natural habitats have been examined for chromosome numbers, three of them for the first time. 2. An up-to-date list of 80Crocus species arranged in taxonomic groups (divisions, sections), according toMaw, is given as an addendum, and the available chromosome numbers are cited. 3.
openaire   +2 more sources

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