Results 151 to 160 of about 405,684 (326)

During heat stress in Myxococcus xanthus , the CdbS PilZ domain protein, along with two PilZ-DnaK chaperones, perturbs chromosome organization and accelerates cell death [PDF]

, 2023
Michael Seidel, Dorota Skotnicka, Timo Glatter, Lotte Søgaard‐Andersen   +3 more
openalex   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Distinct functions of PAXX and MRI during chromosomal end joining

iScience
Summary: A key step of canonical-nonhomologous end joining is synapsis of DNA double-strand break (DSB) ends, which appears to be mediated by both the DNA-PKcs dimer and XLF homodimer. We have examined this process by monitoring end joining (EJ) of blunt
Metztli Cisneros-Aguirre, Felicia Wednesday Lopezcolorado, Xiaoli Ping, Ruby Chen, Jeremy M. Stark   +4 more
doaj   +1 more source

Crumpled polymer with loops recapitulates key features of chromosome organization. [PDF]

Phys Rev X, 2023
Polovnikov KE, Slavov B, Belan S, Imakaev M, Brandão HB, Mirny LA.   +5 more
europepmc   +1 more source

Impact of a selfish B chromosome on chromatin dynamics and nuclear organization in Nasonia [PDF]

, 2012
Megan M. Swim, Kelsey E. Kaeding, Patrick M. Ferree   +2 more
openalex   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

From the archives: Lignin chemistry and vascular cell capacity, chromosome organization in rice meiosis, and circadian clock setting by imbibition. [PDF]

Plant Cell, 2023
Hendrix S.
europepmc   +1 more source

Chromosome organization by one-sided and two-sided loop extrusion [PDF]

, 2019
Edward J. Banigan, Aafke A. van den Berg, Hugo B. Brandão, John F. Marko, Leonid A. Mirny   +4 more
openalex   +1 more source

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

The ubiquitin-proteasome system regulates meiotic chromosome organization. [PDF]

Proc Natl Acad Sci U S A, 2022
Yang X, Song M, Wang Y, Tan T, Tian Z, Zhai B, Yang X, Tan Y, Cao Y, Dai S, Wang S, Zhang L.   +11 more
europepmc   +1 more source