Results 171 to 180 of about 234,024 (306)

The Topography of Chromosome Replication in Yeast

Cold Spring Harbor Symposia on Quantitative Biology, 1993
B J, Brewer, J D, Diller, K L, Friedman, K M, Kolor, M K, Raghuraman, W L, Fangman   +5 more
openaire   +2 more sources

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Dbf4-dependent kinase finetunes Ino80 function at chromosome replication origins. [PDF]

Nat Commun
Bansal P, Lahiri S, Kumar CN, Furtmeier J, Spechtenhauser L, Galanti L, Barba Tena JD, Chacin E, Linder G, Ortíz-Bazán MÁ, Müller M, Vizjak P, Straub T, Mueller-Planitz F, Stigler J, Aguilera A, Gómez-González B, Pfander B, Korber P, Imhof A, Kurat CF.   +20 more
europepmc   +1 more source

A structural view of the initiators for chromosome replication. [PDF]

Curr Opin Struct Biol, 2018
On KF, Jaremko M, Stillman B, Joshua-Tor L.   +3 more
europepmc   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

SMC ensures efficient chromosome replication and oriC positioning during Streptomyces spore germination. [PDF]

Sci Rep
Pawlikiewicz K, Strzałka A, Nurek A, Donczew M, Gierlikowska A, Gongerowska-Jac M, Szafran MJ, Jakimowicz D.   +7 more
europepmc   +1 more source

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

The Bacillus subtilis putative LysR-type transcriptional regulator YybE and its connection to chromosome replication and segregation. [PDF]

Access Microbiol
Koh A.
europepmc   +1 more source

Mathematical description of eukaryotic chromosome replication. [PDF]

Proc Natl Acad Sci U S A, 2019
Li H, O'Donnell ME.
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source