Results 171 to 180 of about 74,687 (303)

Direct interaction between MreB and the RodA‐PBP2 complex organizes lateral cell wall synthesis in Escherichia coli

open access: yesmLife, EarlyView.
Abstract The elongasome, or the Rod complex, orchestrates lateral peptidoglycan (PG) synthesis in many rod‐shaped bacteria. It consists of the actin‐like protein MreB, the PG synthase RodA‐PBP2 complex, as well as MreCD and RodZ. Although the loss or disruption of any elongasome component results in a loss of rod shape, previous studies found that a ...
Rui Zhan   +5 more
wiley   +1 more source

Genetic diversity of collaborative cross mice enables the establishment of a novel <i>Chlamydia muridarum</i> female genital tract infection model. [PDF]

open access: yesInfect Immun
Darville T   +11 more
europepmc   +1 more source

Décryptage du site crtS de Vibrio cholerae et de son rôle dans la réplication coordonnée des deux chromosomes

open access: yes, 2018
Bacterial genomes are mainly composed of two types of replicons: chromosomes, which are essential, and plasmids. Although most bacteria have only one chromosome, bacteria with secondary chromosomes have arisen independently in several taxa and represent ...
Martins, Francisco de Lemos
core  

Symbiont-mediated feminization imposes unavoidable host fitness costs. [PDF]

open access: yesFront Microbiol
Robinson JD   +3 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

A genome‐integrated CRISPR/Cas12a system enables efficient genetic engineering in Xenorhabdus budapestensis XBD8

open access: yesNew Plant Protection, EarlyView.
We developed a genome‐integrated CRISPR/Cas12a system for Xenorhabdus budapestensis XBD8, which enables precise deletion or replacement of DNA fragments ranging from 379 to 45,168 bp, with a success rate exceeding 90%. Application of this tool for the dynamic regulation of fabclavine‐8 biosynthesis resulted in a 1.90‐fold increase in production ...
Wenfeng Gan   +4 more
wiley   +1 more source

Plasmids serve as vehicles and reservoirs of type VI secretion systems. [PDF]

open access: yesISME Commun
Del Mar Quiñonero-Coronel M   +1 more
europepmc   +1 more source

A transient protoplast expression system for functional gene validation in sugarcane: Focus on drought response and immune pathways

open access: yesNew Plant Protection, EarlyView.
We developed a transient expression system for sugarcane using Guitang 42 culm, suitable for various assays such as GCaMP6‐based calcium imaging. This system revealed that ScNCED3 acts as an early drought response signal, positively regulated by ScPYL4‐12, ScOST1‐12, and ScMPK6‐11.
Dianqi Wu   +10 more
wiley   +1 more source

The loop domains of the E. coli β sliding clamp are required for Hda-dependent inactivation of DnaA. [PDF]

open access: yesGenetics
Ghazy MA   +5 more
europepmc   +1 more source

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