Results 31 to 40 of about 344,430 (215)

Unscheduled DNA synthesis after partial UV irradiation of the cell nucleus [PDF]

, 1979
Cells of an euploid strain of the Chinese hamster synchronized in the G1 phase were microirradiated in the nucleus with a laser UV microbeam (λ = 257 nm) and pulse-labelled with [3H]thymidine. In autoradiographs of cells fixed immediately after the pulse
Berliner, Bostock, Brown, Christian Zorn, Christoph Cremer, Cleaver, Cohen, Comings, Cremer, Cremer, Cremer, Cremer, Deaven, Diaz, Dutrillaux, Ehmann, Feldman, Ghosh, Godin, Harris, Heneen, Hens, Hobarth, Hsu, Johnson, Juricek, Jürgen Zimmer, Loza Bonifaz, Moreno, Moreno, Nichols, Rasmussen, Robards, Sakharov, Sakharov, Schempp, Schwarzacher, Singh, Thomas Cremer, Vogel, Warburton, Werry, Wilkins, Williams, Yatani, Zorn, Zorn, Zorn   +47 more
core   +1 more source

Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
A Bolzer, A Fiebig, BM Skinner, C Federico, CK Lee, D Koehler, Darren K Griffin, DJ Prockop, FA Habermann, FH Gage, G Rettenberger, GA Rohrer, GM Cooper, H Ellegren, H Tanabe, H Tanabe, H Telenius, H Telenius, HA Foster, HA Foster, HA McQueen, HB Sun, Helen A Foster, I Szczerbal, IS Mehta, IS Mehta, J Ferreira, JA Croft, JM Bridger, JM Bridger, JM Craig, JM Craig, Joanna M Bridger, KJ Meaburn, KJ Meaburn, KJ Meaburn, L Mora, L Parada, L Schook, LA Parada, M Cremer, M Cremer, M Ferrari, M Knight, M Kuroda, M Neusser, M Yerle-Bouissou, N Gilbert, O Alexandrova, R Mayer, S Boyle, T Cremer, T Cremer, T Misteli, WA Bickmore, Z Jiang   +55 more
core   +2 more sources

Chromosome Segregation Is Biased by Kinetochore Size [PDF]

, 2018
Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection ...
Aguiar, P, Almeida, A C, Damas, J, Drpic, D, Khodjakov, A, Larkin, D M, Lewin, H A, Maiato, H, Renda, F   +8 more
core   +2 more sources

QTL analysis of novel genomic regions associated with yield and yield related traits in new plant type based recombinant inbred lines of rice (Oryza sativa L.)

BMC Plant Biology, 2012
Background Rice is staple food for more than half of the world’s population including two billion Asians, who obtain 60-70% of their energy intake from rice and its derivatives. To meet the growing demand from human population, rice varieties with higher
Marathi Balram, Guleria Smriti, Mohapatra Trilochan, Parsad Rajender, Mariappan Nagarajan, Kurungara Vinod, Atwal Salwandir, Prabhu Kumble, Singh Nagendra, Singh Ashok   +9 more
doaj   +1 more source

Structural fingerprints of transcription factor binding site regions [PDF]

, 2009
Fourier transforms are a powerful tool in the prediction of DNA sequence properties, such as the presence/absence of codons. We have previously compiled a database of the structural properties of all 32,896 unique DNA octamers.
Christopher Hunter, Collins, Eleanor J. Gardiner, Fickett, Kampa, Packer, Peter Willett, Tiwari, Waterston   +8 more
core   +2 more sources

Reporting Unwelcome Unanticipated Findings of Diagnostic Genomic Studies

Voices in Bioethics, 2014
The introduction of comparative genomic hybridization has revolutionized clinical genetics. It is used as a routine approach to the workup of developmental delays and multiple malformations.1-3 By subdividing chromosomes into their submicroscopic ...
Brian James Hanrahan, Robert Roger Lebel
doaj   +1 more source

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. [PDF]

, 2013
Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger elongation of many gene transcripts.
Alber, Tom, Bao, Katherine, Birnberg, Andrew, Chou, Seemay, Krogan, Nevan J, Schulze-Gahmen, Ursula, Upton, Heather, Zhou, Qiang   +7 more
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

The Gender Gap in Pharmaceutical Research

Voices in Bioethics, 2018
“I did what?!” That’s the question more than 1,350 people asked[*1] when reporting adverse effects of Ambien [1]. The accounts became increasingly bizarre – sleep-eating, sleep-walking, sleep-driving.
Elisabeth Armstrong
doaj   +1 more source

Towards many colors in FISH on 3D-preserved interphase nuclei [PDF]

, 2006
The article reviews the existing methods of multicolor FISH on nuclear targets, first of all, interphase chromosomes. FISH proper and image acquisition are considered as two related components of a single process.
Albiez, H., Benecletti, P. A., Bolzer, A., Cremer, M., Cremer, T., Joffe, B., Müller, Stefan, Solovei, Irina, Speicher, Michael R., Walter, J.   +9 more
core   +1 more source