Results 1 to 10 of about 256,401 (97)

Change in the karyotype of the embryo as a cause of spontaneous abortion in the first trimester

Вісник Харківського Національного Університету Імені В.Н. Каразіна: Серія Біологія, 2021
Currently, one of the most actual health problems in the world is the problem of a spontaneous abortion. Chromosomal abnormalities are one of the main reasons of early abortion, stillbirth or the birth of a child with multiple congenital malformations ...
O. Feskov, I. Feskova, Ye. Zhylkova, V. Rudenko, O. Blazhko   +4 more
doaj   +1 more source

Quality of Blastocysts Created by Embryo Splitting: A Time-Lapse Monitoring and Chromosomal Aneuploidy Study

Cell Journal, 2020
Objective: The aim of this study was to screen the potential of human embryos to develop into expanding blastocysts following in vitro embryo splitting and then assess the quality of the generated blastocysts based on chromosomal characteristics and ...
Marjan Omidi, Mohammad Ali Khalili, Iman Halvaei, Fatemeh Montazeri, Seyed Mehdi Kalantar   +4 more
doaj   +1 more source

Comparison of chromosomal instability of human amniocytes in primary and long-term cultures in AmnioMAX II and DMEM media: A cross-sectional study

International Journal of Reproductive BioMedicine, 2020
Background: The genomic stability of stem cells to be used in cell therapy and other clinical applications is absolutely critical. In this regard, the relationship between in vitro expansion and the chromosomal instability (CIN), especially in human ...
Seyed Mehdi Hoseini, Fateme Montazeri, Maryam Moghaddam-Matin, Ahmad Reza Bahrami, Hassan Heidarian Meimandi, Saeed Ghasemi-Esmailabad, Seyed Mehdi Kalantar   +6 more
doaj   +1 more source

Human ring chromosome registry for cases in the Chinese population: re-emphasizing Cytogenomic and clinical heterogeneity and reviewing diagnostic and treatment strategies

Molecular Cytogenetics, 2018
Background Constitutional ring chromosomes are rare orphan chromosomal disorders. Ring chromosome syndrome featuring growth retardation and mild to intermediate intellectual disability is likely caused by the dynamic behavior of ring chromosome through ...
Qiping Hu, Hongyan Chai, Wei Shu, Peining Li   +3 more
doaj   +1 more source

Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]

, 1992
We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas, Jauch, Anna, Stanyon, Roscoe, Wienberg, Johannes   +3 more
core   +1 more source

The over-representation of binary DNA tracts in seven sequenced chromosomes

BMC Genomics, 2004
Background DNA tracts composed of only two bases are possible in six combinations: A+G (purines, R), C+T (pyrimidines, Y), G+T (Keto, K), A+C (Imino, M), A+T (Weak, W) and G+C (Strong, S).
Yagil Gad
doaj   +1 more source

HUMAN RING CHROMOSOMES - NEW INSIGHTS for THEIR CLINICAL SIGNIFICANCE [PDF]

, 2013
Twenty-nine as yet unreported ring chromosomes were characterized in detail by cytogenetic and molecular techniques. for FISH (fluorescence in situ hybridization) previously published high resolution approaches such as multicolor banding (MCB ...
Albrecht, B., Bhatt, S., Brecevic, L., Dufke, A., Guilherme, Roberta dos Santos, Hamid, A. B., Klein, E., Kosyakova, N., Kulpanovich, A., Liehr, T., Manolakos, E., Morlot, S., Petersen, M. B., Polityko, A., Volleth, M.   +14 more
core   +2 more sources

The Gender Gap in Pharmaceutical Research

Voices in Bioethics, 2018
“I did what?!” That’s the question more than 1,350 people asked[*1] when reporting adverse effects of Ambien [1]. The accounts became increasingly bizarre – sleep-eating, sleep-walking, sleep-driving.
Elisabeth Armstrong
doaj   +1 more source

Multicolour interphase cytogenetics: 24 chromosome probes, 6 colours, 4 layers [PDF]

, 2011
From the late 1980s onwards, the use of DNA probes to visualise sequences on individual chromosomes (fluorescent in-situ hybridisation - FISH) revolutionised the study of cytogenetics.
A.R. Thornhill, Abruzzo, Arnold, Camps, Celeda, Cremer, D. Ioannou, D.K. Griffin, Dauwerse, DeSilva, E.J. Meershoek, Egozcue, Emmerich, Ersfeld, Fiegler, Finch, Finch, Foster, Gabriel, Griffin, Griffin, Griffin, Griffin, Griffin, Handyside, Harper, Harper, Harton, Jauch, Julien, Kallioniemi, Kearns, Kolluri, Langer, Lichter, M. Ellis, Mann, Matsuzaki, Muller, Munne, Munne, Munne, Munne, Nederlof, Nordgren, Olszewska, O’Keefe, Pinkel, Quilter, Rennstam, Roberts, Rodriguez, Rottger, Sbracia, Schardin, Schrock, Speicher, Syvanen, Tempest, Tsuchiya, Walling, Wienberg   +61 more
core   +1 more source

Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells [PDF]

, 2011
Copyright @ 2011 Mehta et al.; licensee BioMed Central Ltd. This article has been made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution License ...
Arican, HD, Bridger, JM, Eskiw, CH, Kill, IR, Mehta, IS   +4 more
core   +2 more sources