Results 11 to 20 of about 160,360 (212)

Comparative chromosome painting discloses homologous Segments in distantly related mammals [PDF]

, 1994
Comparative chromosome painting, termed ZOO-FISH, using DNA libraries from flow sorted human chromosomes 1,16,17 and X, and mouse chromosome 11 discloses the presence of syntenic groups in distantly related mammalian Orders ranging from primates (Homo
A Jauch, A Kallioniemi, A Lima-de-Faria, A Lima-de-Faria, Antonio Lima-de-Faria, B Dutrillaux, C Collins, C Lengauer, C Lengauer, C Lengauer, D Pinkel, D Pinkel, E Göttert, EP Evans, G Schriever-Schwemmer, GP Holmquist, GP Holmquist, H Neitzel, H Scherthan, H Scherthan, Harry Scherthan, Heinz-Ulrich Weier, HP Levy, J Hetzel, J Meyne, J Wienberg, J Wienberg, JA Adegoke, JAM Graves, JG Dauwerse, JW Breneman, K Miashita, Lutz Frönicke, M Klever, M Vooijs, M Yerle, MR Speicher, NE Morton, NG Copeland, P Lichter, R Stanyon, S du Manoir, S Liming, S Luke, S Ohno, SF Nelson, SJ O'Brien, SJ O'Brien, SJ O'Brien, T Ried, T Ried, Thomas Cremer, U Amason, U Arnason, Ulfur Arnason, WA Bickmore, XY Guan   +56 more
core   +1 more source

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis [PDF]

, 2014
Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes.
Anderson, M, Bailey, P, Barbour, A, Bruxner, T, Campbell, P, Christ, A, Fink, J, Gotley, D, Grimmond, S, Harliwong, I, Hayward, N, Holmes, O, Hussey, D, Idrisoglu, S, Kazakoff, S, Krause, L, Lampe, G, Leonard, C, Loffler, K, Lord, R, Manning, S, Miller, D, Nancarrow, D, Newell, F, Nones, K, Nourbakhsh, E, Nourse, C, Patch, A, Pearson, J, Phillips, W, Quek, K, Quinn, M, Reid, L, Simpson, P, Smithers, B, Tang, Y, Waddell, N, Waddell, N, Watson, D, Wayte, N, Whiteman, D, Wilson, P, Wood, S, Xu, Q   +43 more
core   +4 more sources

Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]

, 1984
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
A Chapelle de la, AJ Solari, AJ Solari, BD Young, BR Migeon, C Cremer, CR M�ller, CR M�ller, D Page, DT Denhardt, EMJ Southern, GM Wahl, J Fantes, JBS Haldane, JW Gray, KE Davies, L Zech, LM Kunkel, LM Kunkel, MJ Moses, P Goodfellow, P Leder, P Polani, PK Horan, PL Pearson, PN Dean, PN Dean, PN Goodfellow, PS Burgoyne, PS Gerhard, R Krumlauf, RG Langlois, SP Daiger, T Mohandas, U M�ller   +34 more
core   +1 more source

Structural variation in the chicken genome identified by paired-end next-generation DNA sequencing of reduced representation libraries [PDF]

, 2011
Background Variation within individual genomes ranges from single nucleotide polymorphisms (SNPs) to kilobase, and even megabase, sized structural variants (SVs), such as deletions, insertions, inversions, and more complex rearrangements.
Kerstens, H.H.D., Crooijmans, R.P.M.A., Dibbits, B.W., Vereijken, A., Okimoto, R., Groenen, M.A.M.   +5 more
core   +3 more sources

XSim: Simulation of Descendants from Ancestors with Sequence Data. [PDF]

, 2015
Real or imputed high-density SNP genotypes are routinely used for genomic prediction and genome-wide association studies. Many researchers are moving toward the use of actual or imputed next-generation sequence data in whole-genome analyses.
Cheng, Hao, Fernando, Rohan, Garrick, Dorian   +2 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]

, 2018
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core   +1 more source

UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells [PDF]

, 2012
The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons.
An, JY, de Rooij, DG, Han, DH, Jang, JM, Kim, BY, Kim, E, Kim, TY, Kwon, YT, Lee, MJ, Lee, YJ, Seo, JW, Yoo, YD, Zakrzewska, A   +12 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis [PDF]

, 2005
The genetic system on Trypanosoma brucei has been analysed by generating large numbers of independent progeny clones from two crosses, one between two cloned isolates of Trypanosoma brucei brucei and one between cloned isolates of T. b.
Annette MacLeod, Alison Tweedie, Sarah McLellan, Sonya Taylor, Anneli Cooper, Lindsay Sweeney, C. Michael R. Turner, Andy Tait, Hoare, Gibson, Tibayrenc, MacLeod, MacLeod, MacLeod, Gibson, Turner, Jenni, Sternberg, Gibson, Tait, Gibson, Le Page, Paindovoine, Hope, Su, Su, Martinelli, Culleton, Martinelli, Su, Shirley, Tait, MacLeod, El-Sayed, Hall, Benson, Gaunt, Tait, Gibson, Schweizer, Gibson, Gibson, Hassold, Hide, Van Den Abbeele   +44 more
core   +1 more source