Results 11 to 20 of about 112,898 (258)

A genomewide screen for autism susceptibility loci.

American Journal of Human Genetics, 2001
We report the analysis of 335 microsatellite markers genotyped in 110 multiplex families with autism. All families include at least two “affected” siblings, at least one of whom has autism; the remaining affected sibs carry diagnoses of either Asperger ...
Jianjun Liu, D. Nyholt, P. Magnussen, E. Parano, P. Pavone, D. Geschwind, C. Lord, P. Iversen, J. Hoh, the Autism Genetic Resource Exchange Consortium, J. Ott, T. Gilliam   +11 more
semanticscholar   +3 more sources

A genomewide screen of 345 families for autism-susceptibility loci.

American Journal of Human Genetics, 2003
We previously reported a genomewide scan to identify autism-susceptibility loci in 110 multiplex families, showing suggestive evidence (P < .01) for linkage to autism-spectrum disorders (ASD) on chromosomes 5, 8, 16, 19, and X and showing nominal ...
Amanda L. Yonan, M. Alarcón, R. Cheng, P. Magnusson, S. Spence, A. Palmer, A. Grunn, Suh-Hang Hank Juo, J. Terwilliger, Jianjun Liu, R. Cantor, D. Geschwind, T. Gilliam   +12 more
semanticscholar   +2 more sources

Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]

, 1984
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
Back, W., Cremer, Thomas, Rappold, Gudrun A., Cremer, Christoph, Bogenberger, J., Cooke, H. J.   +5 more
core   +1 more source

On the origin of crossover interference : a chromosome oscillatory movement (COM) model [PDF]

, 2011
Background: It is now nearly a century since it was first discovered that crossovers between homologous parental chromosomes, originating at the Prophase stage of Meiosis I, are not randomly placed.
Maj A Hultén, Hultén, Maj A., Hultén Maj A   +2 more
core   +1 more source

Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells [PDF]

, 2013
Copyright © 2013 The Authors. This article is made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which ...
Themis, M, Anderson, RM, Bridger, JM, Foster, HA, Estrada-Girona, G, Garimberti, E, Hill, MA   +6 more
core   +1 more source

Localization, analysis and evolution of transposed human immunoglobulin VK genes [PDF]

, 1988
The localization of Vκ gene regions to chromosome 2, on which the κ locus is located, and to other chromosomes is described. The Vκ genes that have been transposed to other chromosomes are called orphons.
Klopstock, Thomas, Straubinger, Bernhard, Lötscher, Erika, Zachau, Hans G., Zimmer, Franz-Josef, Jaenichen, Rita, Grzeschik, Karl-Heinz   +6 more
core   +1 more source

Patterns of selective constraints in noncoding DNA of rice [PDF]

, 2007
Background Several studies have investigated the relationships between selective constraints in introns and their length, GC content and location within genes. To date, however, no such investigation has been done in plants.
Peter D Keightley, Fan Longjiang, Wang, Y, Wang Yu, Guo, X, Fan, L, Longjiang Fan, Keightley Peter D, Keightley, Peter, Yu Wang, Guo Xingyi, Xingyi Guo   +11 more
core   +1 more source

Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization [PDF]

, 2011
BACKGROUND The genomics era has produced an arsenal of resources from sequenced organisms allowing researchers to target species that do not have comparable mapping and sequence information.
Tuttle, Elaina M, Michael N Romanov, Jerry B Dodgson, Dodgson, Jerry B, Tuttle Elaina M, Elaina M Tuttle, Romanov, Michael N, Dodgson Jerry B, Romanov Michael N, Gonser Rusty A, Rusty A Gonser, Gonser, Rusty A   +11 more
core   +1 more source

Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis [PDF]

, 2011
Monozygotic (MZ) twin pair discordance for childhood-onset Type 1 Diabetes (T1D) is similar to 50%, implicating roles for genetic and non-genetic factors in the aetiology of this complex autoimmune disease.
Busato, F, Manfras, B, Kerith-rae M, Leslie, R. David, Jörg Tost, Manfras Burkhard, Mohammed I Hawa, Thomas A. Down, Maslau, S, Leslie, RD, Mohammed I. Hawa, Bernhard O Boehm, Beck Stephan, Rakyan, VK, Aden Deeqo, Daunay, A, Maslau Siarhei, Down Thomas A., Dias, Kerith-Rae M., Bell, Christopher G., Rakyan, Vardhman K., Boehm, Bernhard O., Beck, S, Bell Christopher G., Leslie R. David, Charles A. Mein, Charles A Mein, Boehm Bernhard O., Vardhman K Rakyan, Beyan, H, Burkhard Manfras, Christopher G. Bell, Hawa, MI, Kerith-Rae M. Dias, Vardhman K. Rakyan, R David Leslie, Kerith-Rae M Dias, Siarhei Maslau, Hawa Mohammed I., Busato Florence, Deeqo Aden, Bell, CG, Beck, Stephan, Stephan Beck, Bernhard O. Boehm, Busato, Florence, Dias Kerith-Rae M., Tost Jörg, Mein, Charles A., Christopher G Bell, Dias, KRM, Tost, J, Maslau, Siarhei, Hawa, Mohammed I., Daunay, Antoine, R. David Leslie, Florence Busato, Down, Thomas A., Rakyan Vardhman K., Tost, Jörg, Mein, CA, Daunay Antoine, Beyan, Huriya, Down, TA, Boehm, BO, Huriya Beyan, Antoine Daunay, Mein Charles A., Manfras, Burkhard, Thomas A Down, Beyan Huriya, Aden, D, Aden, Deeqo   +72 more
core   +1 more source

Dosage compensation in birds

, 2001
The Z and W sex chromosomes of birds have evolved independently from the mammalian X and Y chromosomes [1]. Unlike mammals, female birds are heterogametic (ZW), while males are homogametic (ZZ).
Bird, Adrian P, Derek McBride, McQueen, H A; id_orcid, Gino Miele, McQueen, Heather A, McBride, Derek, Miele, Gino, McBride, D, Miele, G, Clinton, M, Bird, A P; id_orcid, Heather A McQueen, Michael Clinton, Clinton, Michael, Adrian P Bird   +14 more
core   +1 more source