Condensin IDC has a functional ATPase that is required for X-Chromosome dosage compensation in C. elegans. [PDF]
Chawla B +7 more
europepmc +1 more source
IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong +5 more
wiley +1 more source
Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression. [PDF]
Vukušić K, Tolić IM.
europepmc +1 more source
Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu +4 more
wiley +1 more source
Common variation in meiosis genes shapes human recombination and aneuploidy. [PDF]
Carioscia SA +6 more
europepmc +1 more source
Oocyte–cumulus cell interaction: a key factor in early embryo development
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
A programmable platform enabling targeted chromosome substitution and cross-species stability profiling. [PDF]
Shi L +5 more
europepmc +1 more source
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
Selfish chromosomes exploit a germline checkpoint to eliminate competing gametes. [PDF]
Ridges JT +9 more
europepmc +1 more source

