On the origin of crossover interference : a chromosome oscillatory movement (COM) model [PDF]
Background: It is now nearly a century since it was first discovered that crossovers between homologous parental chromosomes, originating at the Prophase stage of Meiosis I, are not randomly placed.
Maj A Hultén +2 more
core +1 more source
Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells [PDF]
Copyright © 2013 The Authors. This article is made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which ...
Themis, M +6 more
core +1 more source
Localization, analysis and evolution of transposed human immunoglobulin VK genes [PDF]
The localization of Vκ gene regions to chromosome 2, on which the κ locus is located, and to other chromosomes is described. The Vκ genes that have been transposed to other chromosomes are called orphons.
Klopstock, Thomas +6 more
core +1 more source
Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization [PDF]
BACKGROUND The genomics era has produced an arsenal of resources from sequenced organisms allowing researchers to target species that do not have comparable mapping and sequence information.
Tuttle, Elaina M +11 more
core +1 more source
Orphan CpG islands identify numerous conserved promoters in the mammalian genome [PDF]
This work was funded by grants from the Wellcome Trust (077224; http://www.wellcome.ac.uk/) and the Medical Research Council (G0800026; http:// www.mrc.ac.uk/index.htm).CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of ...
Gruenewald-Schneider, Ulrike +45 more
core +1 more source
The value of avian genomics to the conservation of wildlife [PDF]
Background: Genomic studies in non-domestic avian models, such as the California condor and white-throated sparrow, can lead to more comprehensive conservation plans and provide clues for understanding mechanisms affecting genetic variation, adaptation ...
Hickenbotham, Matthew T +33 more
core +1 more source
Acrocentric bivalents positioned preferentially nearby to the XY pair in metaphase i human spermatocytes [PDF]
Objective: To analyze whether the preferential proximity between acrocentric bivalents and the XY pair described at pachytene was maintained in metaphase I human spermatocytes. Design: Proximity frequencies of autosomic bivalents to the sex bivalent were
Vidal, Francesca +2 more
core +1 more source
Nonrandom distribution of metaphase AgNOR staining patterns on human acrocentric chromosomes.
The metaphase nucleolar organizer regions (NORs) contain ribosomal genes associated with proteins such as upstream binding factor (UBF) and RNA polymerase I (RPI). These genes are clustered in 10 loci of the human acrocentric chromosomes (13, 14, 15, 21,
O'Donohue, M. F. +10 more
core +1 more source
Patterns of selective constraints in noncoding DNA of rice [PDF]
Background Several studies have investigated the relationships between selective constraints in introns and their length, GC content and location within genes. To date, however, no such investigation has been done in plants.
Peter D Keightley +11 more
core +1 more source
Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis [PDF]
Monozygotic (MZ) twin pair discordance for childhood-onset Type 1 Diabetes (T1D) is similar to 50%, implicating roles for genetic and non-genetic factors in the aetiology of this complex autoimmune disease.
Busato, F +72 more
core +1 more source

