Results 11 to 20 of about 71,445,035 (215)

Differences in the localization and morphology of chromosomes in the human nucleus [PDF]

, 1999
Using fluorescence in situ hybridization we show striking differences in nuclear position, chromosome morphology, and interactions with nuclear substructure for human chromosomes 18 and 19.
Perry, P, Boyle, S, Bridger, JM, Croft, J, Bickmore, WA, Teague, P   +5 more
core   +7 more sources

Sorting of chromosomes by magnetic separation [PDF]

, 1988
Chromosomes were isolated from Chinese hamster x human hybrid cell lines containing four and nine human chromosomes. Human genomic DNA was biotinylated by nick translation and used to label the human chromosomes by in situ hybridization in suspension ...
Dudin, Gertrud, Steegmayer, Ernst W., Cremer, Thomas, E. Howell, Kathryn, Vogt, Peter, Schnitzer, Haide, Cremer, Christoph, Diaz, Eduardo   +7 more
core   +1 more source

Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes [PDF]

, 2010
Copyright: © 2010 Stimpson et al.Genome rearrangement often produces chromosomes with two centromeres (dicentrics) that are inherently unstable because of bridge formation and breakage during cell division. However, mammalian dicentrics, and particularly
Sullivan, Beth A., Sullivan, Beth A, Karen E. Hayden, Kaitlin M. Stimpson, Beth A Sullivan, Bridger Joanna M., Song, IY, Sullivan, BA, Ihn Young Song, Beth A. Sullivan, Karen E Hayden, Hayden, Karen E., Jauch, A, Bridger, Joanna M., Joanna M Bridger, Joanna M. Bridger, Hayden, Karen E, Song Ihn Young, Jauch, Anna, Holtgreve-Grez, Heidi, Heidi Holtgreve-Grez, Holtgreve-Grez Heidi, Stimpson, Kaitlin M, Stimpson, KM, Kaitlin M Stimpson, Anna Jauch, Bridger, JM, Jauch Anna, Bridger, Joanna M, Stimpson Kaitlin M., Sullivan Beth A., Song, Ihn Young, Hayden Karen E., Hayden, KE, Holtgreve-Grez, H, Stimpson, Kaitlin M.   +35 more
core   +2 more sources

Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes [PDF]

, 2005
Studies of higher-order chromatin arrangements are an essential part of ongoing attempts to explore changes in epigenome structure and their functional implications during development and cell differentiation.
Kreth Gregor, Michael R Speicher, Bolzer Andreas, Cremer Christoph, Kreth, G., Andreas Bolzer (83), Cremer, Christoph, Eils, R., Christoph Cremer, Christoph Cremer (91), Fauth Christine, Irina Solovei, Solovei, Irina, Daniela Koehler, Gregor Kreth (84), Eils, Roland, Gregor Kreth, Kaan Saracoglu, Bolzer, Andreas, Koehler Daniela, Irina Solovei (85), Fauth, C., Thomas Cremer (93), Bolzer, A., Speicher, Michael R., Müller Stefan, Solovei Irina, Müller, Stefan, Saracoglu, Kaan, Stefan Müller, Fauth, Christine, Roland Eils (90), Kreth, Gregor, Cremer Thomas, Koehler, D., Stefan Müller (89), Michael R Speicher (27551), Thomas Cremer, Solovei, I., Roland Eils, Müller, S., Cremer, C., Koehler, Daniela, Speicher, M.R., Eils Roland, Speicher Michael R, Cremer, Thomas, Andreas Bolzer, Daniela Koehler (86), Christine Fauth (88), Cremer, T., Saracoglu Kaan, Christine Fauth, Kaan Saracoglu (87), Saracoglu, K.   +54 more
core   +1 more source

Holocentric Chromosomes of Luzula elegans Are Characterized by a Longitudinal Centromere Groove, Chromosome Bending, and a Terminal Nucleolus Organizer Region [PDF]

, 2011
The structure of holocentric chromosomes was analyzed in mitotic cells of Luzula elegans. Light and scanning electron microscopy observations provided evidence for the existence of a longitudinal groove along each sister chromatid.
Houben, A., Kumke, K., K. Nagaki, Murata, M., S. Heckmann, G. Wanner, K. Kumke, Wanner, Gerhard, Heckmann, S., Nagaki, Kiyotaka, Schroeder-Reiter, E., L. Ma, Ma, L., E. Schroeder-Reiter, M. Murata, A. Houben   +15 more
core   +1 more source

Characterization of two marker chromosomes in a patient with acute nonlymphocytic leukemia by two-color fluorescence in situ hybridization [PDF]

, 1993
A patient with acute nonlymphocytic leukemia (ANLL), M5b according to French-American-British (FAB) classification, showed monosomy 16, an extra 1p−, and a 21q+. These derivative chromosomes could not be defined by GTG-banding.
Speicher, Michael R., Cremer, Thomas, Taniwaki, Masafumi, Jauch, Anna, Popp, Susanne, Lengauer, Christoph   +5 more
core   +1 more source

Painting of human chromosomes with probes generated from hybrid cell lines by PCR with Alu and L1 primers [PDF]

, 1990
Specific amplification of human sequences of up to several kb length has recently been accomplished in man-hamster and man-mouse somatic hybrid cell DNA by IRS-PCR (interspersed repetitive sequence — polymerase chain reaction).
Riethman, Harold C., Cremer, Thomas, Lengauer, Christoph   +2 more
core   +1 more source

Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla [PDF]

, 1992
The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined ...
Stanyon, Roscoe, Cremer, Thomas, Romagno, D., Wienberg, Johannes, A. Jauch, T. Cremer, Bigoni, F., J. Wienberg, F. Bigoni, D. Romagno, Jauch, Anna, R. Stanyon   +11 more
core   +1 more source

Overcoming Artificial Structures in Resolution-Enhanced Hi-C Data by Signal Decomposition and Multi-Scale Attention. [PDF]

Adv Sci (Weinh)
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Li Q, Li KY, Nicoletti C, Tsui SK, Puri PL, Cao Q, Yip KY.   +6 more
europepmc   +2 more sources

Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction [PDF]

, 1992
Non-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid
Dunham, Ian, Cremer, Thomas, Terry Featherstone, Christoph Lengauer, Featherstone, Terry, Lan Dunham, Lengauer, Christoph, Thomas Cremer   +7 more
core   +1 more source