Natural selection reduced diversity on human y chromosomes. [PDF]
The human Y chromosome exhibits surprisingly low levels of genetic diversity. This could result from neutral processes if the effective population size of males is reduced relative to females due to a higher variance in the number of offspring from males
Melissa A Wilson Sayres +2 more
doaj +13 more sources
Novel gene acquisition on carnivore Y chromosomes. [PDF]
Despite its importance in harboring genes critical for spermatogenesis and male-specific functions, the Y chromosome has been largely excluded as a priority in recent mammalian genome sequencing projects.
William J Murphy +6 more
doaj +2 more sources
Natural Selection on Human Y Chromosomes [PDF]
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Chuan-Chao Wang, Li Jin, Hui Li
openaire +3 more sources
Application of the FISH Technique to Visualize Sex Chromosomes in Domestic Cat Spermatozoa
Fluorescence in situ hybridization is a molecular cytogenetics technique that enables the visualization of chromosomes in cells via fluorescently labeled molecular probes specific to selected chromosomes.
Barbara Kij-Mitka +6 more
doaj +1 more source
The quiescent X, the replicative Y and the Autosomes
From the analysis of the mutation spectrum in the 2,504 sequenced human genomes from the 1000 genomes project (phase 3), we show that sexual chromosomes (X and Y) exhibit a different proportion of indel mutations than autosomes (A), ranking them X>A>Y ...
Achaz, Guillaume +2 more
doaj +1 more source
Despite its central role in sex determination, genetic analysis of the Y chromosome has been slow. This poor progress has been due to the paucity of available genetic markers. Whereas the X chromosome is known to include at least 100 functional genetic loci, only three or four loci have been ascribed to the Y chromosome and even the existence of ...
P, Goodfellow, S, Darling, J, Wolfe
openaire +2 more sources
An analysis of Y-chromosome microdeletion in infertile Korean men with severe oligozoospermia or azoospermia [PDF]
Purpose: Infertility affects 10% to 15% of couples, and male factor accounts for 50% of the cases. The relevant male genetic factors, which account for at least 15% of male infertility, include Y-chromosome microdeletions.
Tae Ho Lee +5 more
doaj +1 more source
Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]
We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas +3 more
core +1 more source
Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes [PDF]
Two cloned repetitive DNA probes, pXBR and CY1, which bind preferentially to specific regions of the human X and Y chromosome, respectively, were used to study the distribution of the sex chromosomes in human lymphocyte nuclei by in situ hybridization ...
C. R. M�ller +30 more
core +1 more source
Human male meiotic sex chromosome inactivation. [PDF]
In mammalian male gametogenesis the sex chromosomes are distinctive in both gene activity and epigenetic strategy. At first meiotic prophase the heteromorphic X and Y chromosomes are placed in a separate chromatin domain called the XY body.
Marieke de Vries +6 more
doaj +1 more source

