Results 11 to 20 of about 304,583 (304)

Evidence of extensive non-allelic gene conversion among LTR elements in the human genome [PDF]

, 2016
Long Terminal Repeats (LTRs) are nearly identical DNA sequences found at either end of Human Endogenous Retroviruses (HERVs). The high sequence similarity that exists among different LTRs suggests they could be substrate of ectopic gene conversion events.
CRUCIANI, Fulvio, D'ATANASIO, EUGENIA, Fantini, Gloria, Sellitto, Daniele, TROMBETTA, BENIAMINO   +4 more
core   +1 more source

Chimpanzee and Human Y Chromosomes Are Remarkably Divergent in Structure and Gene Content [PDF]

, 2009
LetterThe human Y chromosome began to evolve from an autosome hundreds of millions of years ago, acquiring a sex-determining function and undergoing a series of inversions that suppressed crossing over with the X chromosome[1, 2].
AF Dixson, B Charlesworth, B Charlesworth, Barbara J. Trask, BT Lahn, CL Peichel, CT Yohn, Cynthia Friedman, D Bachtrog, D Bachtrog, DA Filatov, David C. Page, DC Page, Devin P. Locke, Elaine R. Mardis, H Skaletsky, H Watanabe, HC Mefford, Helen Skaletsky, J Lange, Jennifer F. Hughes, JF Hughes, JF Hughes, LW Hillier, Patrick J. Minx, R Saxena, RF Yeh, Richard K. Wilson, Robert S. Fulton, S Repping, S Repping, S Repping, S Rozen, S Steinemann, Saskia K. M. van Daalen, Sean D. McGrath, Sjoerd Repping, Steve Rozen, T Kuroda-Kawaguchi, Tatyana Pyntikova, Tina A. Graves, Wesley C. Warren, WJ Murphy, WR Rice, Y Kuroki, Z Liu   +45 more
core   +1 more source

Population growth of human Y chromosomes: a study of Y chromosome microsatellites [PDF]

Molecular Biology and Evolution, 1999
We use variation at a set of eight human Y chromosome microsatellite loci to investigate the demographic history of the Y chromosome. Instead of assuming a population of constant size, as in most of the previous work on the Y chromosome, we consider a model which permits a period of recent population growth.
J K, Pritchard, M T, Seielstad, A, Perez-Lezaun, M W, Feldman   +3 more
openaire   +2 more sources

Chromosomal in situ suppression hybridization of human gonosomes and autosomes and its use in clinical cytogenetics [PDF]

, 1990
DNA libraries from sorted human gonosomes were used selectively to stain the X and Y chromosomes in normal and aberrant cultured human cells by chromosomal in situ suppression (CISS-) hybridization.
Cremer, Thomas, Daumer, C., Jauch, Anna, Lichter, Peter, Murken, J., Schroeder-Kurth, T.   +5 more
core   +1 more source

Flow Sorting Enrichment and Nanopore Sequencing of Chromosome 1 From a Chinese Individual

Frontiers in Genetics, 2020
Sorting of individual chromosomes by Flow Cytometry (flow-sorting) is an enrichment method to potentially simplify genome assembly by isolating chromosomes from the context of the genome.
Lukas F. K. Kuderna, Manuel Solís-Moruno, Manuel Solís-Moruno, Laura Batlle-Masó, Laura Batlle-Masó, Eva Julià, Eva Julià, Esther Lizano, Roger Anglada, Erika Ramírez, Alex Bote, Marc Tormo, Marc Tormo, Tomàs Marquès-Bonet, Tomàs Marquès-Bonet, Tomàs Marquès-Bonet, Tomàs Marquès-Bonet, Tomàs Marquès-Bonet, Òscar Fornas, Òscar Fornas, Ferran Casals   +20 more
doaj   +1 more source

Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators [PDF]

, 2017
After birds diverged from mammals, different ancestral autosomes evolved into sex chromosomes in each lineage. In birds, females are ZW and males are ZZ, but in mammals females are XX and males are XY.
A Cockwell, A Dunford, A Krasikova, AE Wright, AK Fridolfsson, Andrew G Clark, B Charlesworth, B Papp, B Vicoso, BT Lahn, BT Lahn, C Zweier, Colin Kremitzki, D Slonim, D Zhao, Daniel W Bellott, David C Page, Devin Locke, DW Bellott, DW Bellott, EB Hook, Elena Gaginskaya, ET Tonkin, F Cunningham, G Li, H Skaletsky, Helen Skaletsky, HK Moghadam, HP Yazdi, I Korf, I Nanda, I Skromne, I Solovei, J Alföldi, J Cocquet, J Cocquet, J Merkin, J Zhang, JA St John, JE Mank, JF Hughes, JF Hughes, JL Mueller, JL Mueller, JS Amberger, JW Wallis, KL Ayers, L Smeds, L Yan, Laura Brown, LJ Handley, M Morisson, MA White, MD Robinson, MK Lee, MT Ross, N Chen, N Huang, Nancy Chen, Natalia Koutseva, NL Bray, NS Fechheimer, P Flicek, PE Boardman, Q Zhou, RE Green, Richard K Wilson, RJ Aitken, S Li, SB Hedges, SE Bloom, SJ Conway, Svetlana Galkina, T Hassold, T Hori, Tatyana Pyntikova, Tina Graves, Ting-Jan Cho, VB Kaiser, Wesley C Warren, Y Itoh, Y Saitoh, YQ Soh   +82 more
core   +2 more sources

Frequent gene conversion events between the X and Y homologous chromosomal regions in primates

BMC Evolutionary Biology, 2010
Background Mammalian sex-chromosomes originated from a pair of autosomes. A step-wise cessation of recombination is necessary for the proper maintenance of sex-determination and, consequently, generates a four strata structure on the X chromosome.
Hirai Hirohisa, Satta Yoko, Iwase Mineyo, Hirai Yuriko, Takahata Naoyuki   +4 more
doaj   +1 more source

Unique signatures of natural background radiation on human Y chromosomes from Kerala, India. [PDF]

PLoS ONE, 2009
BackgroundThe most frequently observed major consequences of ionizing radiation are chromosomal lesions and cancers, although the entire genome may be affected.
Sanjay Premi, Jyoti Srivastava, Sebastian Padinjarel Chandy, Sher Ali   +3 more
doaj   +1 more source

No evidence for a second evolutionary stratum during the early evolution of mammalian sex chromosomes. [PDF]

PLoS ONE, 2012
Mammalian sex chromosomes originated from a pair of autosomes, and homologous genes on the sex chromosomes (gametologs) differentiated through recombination arrest between the chromosomes.
Yukako Katsura, Yoko Satta
doaj   +1 more source

Continued colonization of the human genome by mitochondrial DNA. [PDF]

PLoS Biology, 2004
Integration of mitochondrial DNA fragments into nuclear chromosomes (giving rise to nuclear DNA sequences of mitochondrial origin, or NUMTs) is an ongoing process that shapes nuclear genomes.
Miria Ricchetti, Fredj Tekaia, Bernard Dujon   +2 more
doaj   +1 more source