Frequent gene conversion events between the X and Y homologous chromosomal regions in primates
Background Mammalian sex-chromosomes originated from a pair of autosomes. A step-wise cessation of recombination is necessary for the proper maintenance of sex-determination and, consequently, generates a four strata structure on the X chromosome.
Hirai Hirohisa +4 more
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Unique signatures of natural background radiation on human Y chromosomes from Kerala, India. [PDF]
BackgroundThe most frequently observed major consequences of ionizing radiation are chromosomal lesions and cancers, although the entire genome may be affected.
Sanjay Premi +3 more
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No evidence for a second evolutionary stratum during the early evolution of mammalian sex chromosomes. [PDF]
Mammalian sex chromosomes originated from a pair of autosomes, and homologous genes on the sex chromosomes (gametologs) differentiated through recombination arrest between the chromosomes.
Yukako Katsura, Yoko Satta
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Continued colonization of the human genome by mitochondrial DNA. [PDF]
Integration of mitochondrial DNA fragments into nuclear chromosomes (giving rise to nuclear DNA sequences of mitochondrial origin, or NUMTs) is an ongoing process that shapes nuclear genomes.
Miria Ricchetti +2 more
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Selective single molecule sequencing and assembly of a human Y chromosome of African origin
Due to various structural and sequence complexities, the human Y chromosome is challenging to sequence and characterize. Here, the authors develop a strategy to sequence native, unamplified flow sorted Y chromosomes with a nanopore sequencing platform ...
Lukas F. K. Kuderna +15 more
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Chimpanzees and humans are genetically very similar, with the striking exception of their Y chromosomes, which have diverged tremendously. The male-specific region (MSY), representing the greater part of the Y chromosome, is inherited from father to son ...
Eskeatnaf Mulugeta Achame +3 more
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A comparative of G-banded chromosome of Assam Macaque (Macaca assamensis) and relationship to human (Homo sapiens) [PDF]
This research was the first to report a comparative analysis of G-banded chromosome of Assam macaque, Macaca assamensis (Primate, Cercopithecidae) and relationship to human, Homo sapiens (Primate, Hominidae).
Bunjongrat, R. +3 more
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Comparative chromosome G-banding analysis of long-tailed macaque (Macaca fascicularis) and relationship to human (Homo sapiens) [PDF]
This research is the first report of the comparative chromosome between long-tailed macaque (Macaca fascicularis) and human (Homo sapiens) using G-banding. Blood samples from four male and three female macaques were used.
Alongkoad Tanomtong +2 more
doaj
Gender-specific characteristics of hypertrophic response in cardiomyocytes derived from human embryonic stem cells [PDF]
Introduction: Gender-specific phenotypes of the heart were reported with respect to both physiology and pathology. While most differences were associated with the sex hormones, differential expression of genes received special attention, particularly X-Y
Shiva Ahmadvand +3 more
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Background The X and Y sex chromosomes are conspicuous features of placental mammal genomes. Mammalian sex chromosomes arose from an ordinary pair of autosomes after the proto-Y acquired a male-determining gene and degenerated due to suppression of X-Y ...
Mácha Jaroslav +6 more
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