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The human Y chromosome: a masculine chromosome

Current Opinion in Genetics & Development, 2006
Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production.
Michiel J, Noordam, Sjoerd, Repping
openaire   +4 more sources

HUMAN CHROMOSOME Y AND SRY

Cell Biology International, 1996
AbstractThe precise location of the SRY gene on the human Y chromosome has been revealed through studies of sex reversal cases involving deletion, cross‐linking and mutations of the SRY gene. Its DNA sequence and mechanism of action are being understood.
V C, Shah, V, Smart
openaire   +2 more sources

Evolution of human Y-chromosome DNA

Chromosoma, 1982
We have used human male-specific 3.4 kb Hae III restriction endonuclease fragments to explore the evolutionary history of man's Y-chromosome. We have identified four sets of reiterated sequences on the basis of their relative sequence homology with autosomal DNA.
L M, Kunkel, K D, Smith
openaire   +2 more sources

The Y Chromosome in Human Spermatozoa

Nature, 1970
ATTEMPTS have been made to distinguish between spermatozoa of mammals containing either an X or a Y chromosome by looking for differences in size and surface properties of the two classes of cells (see refs. 1 and 2 for reviews), but the results of such approaches are equivocal.
P, Barlow, C G, Vosa
openaire   +2 more sources

Subdivision of the human Y chromosome

Human Genetics, 1974
The normal human Y chromosome was subdivided into 6 distinct bands by Q, C bandings and microdensitometric tracing. The best results were obtained from chromosomes not fully condensed. The results reveal that at late prophase the Y can be subdivided in 1 single unstained band in short arm 5 bands in the long arm.
S M, Jalal   +3 more
openaire   +2 more sources

Human Y-Chromosome-Specific Reiterated DNA

Science, 1976
Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [ 3 H]DNA prepared from men and excess DNA from women. These highly purified labeled sequences reassociate only with DNA from individuals with a Y chromosome.
L M, Kunkel, K D, Smith, S H, Boyer
openaire   +2 more sources

Human evolution and the Y chromosome

Current Opinion in Genetics & Development, 1996
The past two years have seen the increased study of Y-chromosome polymorphisms and their relationship to human evolution and variation. Low Y-chromosome sequence diversity indicates that the common ancestor of all extant Y chromosomes lived relatively recently and the consensus of estimates of time to the most recent common ancestor concur with ...
R J, Mitchell, M F, Hammer
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Mapping the human Y chromosome

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1988
This paper reviews past and present trends in mapping the human Y chromosome. So far, mapping has essentially used a combination of cytogenetic and molecular analyses of Y-chromosomal anomalies and sex reversal syndromes. This deletion mapping culminated recently in the isolation of the putative sex-determining locus TDF
openaire   +2 more sources

The Human Y Chromosome

2017
Structure of the Y chromosome Evolution of Y chromosome from autosomes Genes on human Y chromosome SRY gene and sex determination Azoospermia factors Copy number variations Functions Y chromosome-linked ...
Manish Jain   +3 more
openaire   +1 more source

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