The use of DAPI fluorescence lifetime imaging for investigating chromatin condensation in human chromosomes [PDF]
Chromatin undergoes dramatic condensation and decondensation as cells transition between the different phases of the cell cycle. The organization of chromatin in chromosomes is still one of the key challenges in structural biology.
Botchway, S +4 more
core +1 more source
Evolution of Genomic Structures on Mammalian Sex Chromosomes [PDF]
Throughout mammalian evolution, recombination between the two sex chromosomes was suppressed in a stepwise manner. It is thought that the suppression of recombination led to an accumulation of deleterious mutations and frequent genomic rearrangements on ...
IWASE Mineyo +3 more
core +2 more sources
Selective single molecule sequencing and assembly of a human Y chromosome of African origin
Due to various structural and sequence complexities, the human Y chromosome is challenging to sequence and characterize. Here, the authors develop a strategy to sequence native, unamplified flow sorted Y chromosomes with a nanopore sequencing platform ...
Lukas F. K. Kuderna +15 more
doaj +1 more source
Chimpanzees and humans are genetically very similar, with the striking exception of their Y chromosomes, which have diverged tremendously. The male-specific region (MSY), representing the greater part of the Y chromosome, is inherited from father to son ...
Eskeatnaf Mulugeta Achame +3 more
doaj +1 more source
Multicolour interphase cytogenetics: 24 chromosome probes, 6 colours, 4 layers [PDF]
From the late 1980s onwards, the use of DNA probes to visualise sequences on individual chromosomes (fluorescent in-situ hybridisation - FISH) revolutionised the study of cytogenetics.
A.R. Thornhill +61 more
core +1 more source
A comparative of G-banded chromosome of Assam Macaque (Macaca assamensis) and relationship to human (Homo sapiens) [PDF]
This research was the first to report a comparative analysis of G-banded chromosome of Assam macaque, Macaca assamensis (Primate, Cercopithecidae) and relationship to human, Homo sapiens (Primate, Hominidae).
Bunjongrat, R. +3 more
doaj
Gender-specific characteristics of hypertrophic response in cardiomyocytes derived from human embryonic stem cells [PDF]
Introduction: Gender-specific phenotypes of the heart were reported with respect to both physiology and pathology. While most differences were associated with the sex hormones, differential expression of genes received special attention, particularly X-Y
Shiva Ahmadvand +3 more
doaj +1 more source
Comparative chromosome G-banding analysis of long-tailed macaque (Macaca fascicularis) and relationship to human (Homo sapiens) [PDF]
This research is the first report of the comparative chromosome between long-tailed macaque (Macaca fascicularis) and human (Homo sapiens) using G-banding. Blood samples from four male and three female macaques were used.
Alongkoad Tanomtong +2 more
doaj
A family case of fertile human 45,X,psu dic(15;Y) males [PDF]
We report on a familial case including four male probands from three generations with a 45,X,psu dic(15;Y)(p11.2;q12) karyotype. 45,X is usually associated with a female phenotype and only rarely with maleness, due to translocation of small Y chromosomal
Andersson M +29 more
core +1 more source
Background The X and Y sex chromosomes are conspicuous features of placental mammal genomes. Mammalian sex chromosomes arose from an ordinary pair of autosomes after the proto-Y acquired a male-determining gene and degenerated due to suppression of X-Y ...
Mácha Jaroslav +6 more
doaj +1 more source

