Results 181 to 190 of about 9,449,306 (346)

Optimized dicentric chromosome dose-response curves with centromere probes improve low-dose radiation biodosimetry. [PDF]

Sci Rep
Jeong MH, Choi HS, Jeong SK, Kang YR, Lee CG, Kim HJ, Kye YU, Baek JH, Park MT, Kim JS, Oh SJ, Jo WS.   +11 more
europepmc   +1 more source

Heterogeneity in telomere length of human chromosomes.

Human Molecular Genetics, 1996
P. Lansdorp, N. Verwoerd, F. M. Rijke, V. Dragowska, M. Little, R. Dirks, A. Raap, H. Tanke   +7 more
semanticscholar   +1 more source

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

Advanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang, Rui Yan, Jing Guo, Mengyao Wang, Xin Cheng, Fan Zhang, Tianzi Guo, Xin Long, Fan Guo, Dan Liang   +9 more
wiley   +1 more source

Impact of sperm fractionation on chromosome positioning, chromatin integrity, DNA methylation, and hydroxymethylation level. [PDF]

Cell Mol Biol Lett
Graczyk Z, Kostyk J, Pospieszna J, Myslicka Z, Kamieniczna M, Fraczek M, Olszewska M, Kurpisz M.   +7 more
europepmc   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Capturing aberrant cell behaviors producing defects in human embryos via live imaging. [PDF]

Sci Adv
Akizawa H, Domingo-Muelas A, Pardo-Figuerez M, Hernandez B, Ardestani G, Skory RM, Venturas M, Tetlak P, Bissiere S, Sakkas D, Simon C, Plachta N.   +11 more
europepmc   +1 more source

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

Science, 2015
E. Blackburn, E. Epel, Jue Lin
semanticscholar   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Human selection maintains karyotype integrity of highly unstable genomic cultivated autotetraploid potato (<i>Solanum tuberosum</i>). [PDF]

Sci Adv
Yang L, Bai Y, Chao G, Zhao K, Xu J, Sun M, Zhang H, Niu Y, Li K, Xiong Z, Cao Y, Wang F, Hai B, Cao C, Yin Y, Lin T, Wang Y, Gong X, Wu L, Jiang J, Xiong Z.   +20 more
europepmc   +1 more source

Chromosome conformation elucidates regulatory relationships in developing human brain

Nature, 2016
H. Won, L. Torre-Ubieta, J. Stein, N. Parikshak, Jerry Huang, Carli K. Opland, M. Gandal, G. J. Sutton, F. Hormozdiari, D. Lu, Changhoon Lee, E. Eskin, I. Voineagu, J. Ernst, D. Geschwind   +14 more
semanticscholar   +1 more source