Results 121 to 130 of about 1,551,359 (398)

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

open access: yesMolecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Evaluación cariotípica de un grupo de búfalos en Fredonia, Antioquia (Colombia) Cariotypic evaluation of buffalos in a farm in Fredonia, Antioquia, Colombia

open access: yesRevista Colombiana de Ciencias Pecuarias, 2006
En el presente trabajo se realizó la caracterización citogenética de búfalos por bandas R-replicativas, con el fin de conocer su número cromosómico, para así realizar su clasificación ya sea como búfalo de río o de pantano. También se buscó la existencia
Mónika M Alzate   +2 more
doaj  

(Ovo-)viviparity in the darkling beetle, Alegoria castelnaui (Tenebrioninae: Ulomini), from Guadeloupe

open access: yesEuropean Journal of Entomology, 2010
In the course of cytogenetic studies on Alegoria castelnaui Fleutiaux & Sallé 1889 (Coleoptera: Tenebrionidae: Tenebrioninae: Ulomini) from Guadeloupe, a number of adult specimens were dissected.
Anne Marie DUTRILLAUX   +2 more
doaj   +1 more source

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

open access: yes, 2020
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U.   +6 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Chromosomal characterization of Hyla bischoffi and Hyla guentheri (Anura, Hylidae)

open access: yesPhyllomedusa: Journal of Herpetology, 2004
Hyla bischoffi and H. guentheri share some morphological and call characters with the H. pulchella and H. polytaenia groups. The inclusion of these two species in one of these two groups is still controversial. This study showed that both species have 2n
Simone C. Raber   +4 more
doaj  

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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