Results 121 to 130 of about 1,562,582 (397)

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

open access: yes, 2020
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U.   +6 more
core   +1 more source

Unanswered Questions Regarding Sex and BMP/TGF-β Signaling

open access: yesJournal of Developmental Biology, 2018
Crosstalk between the BMP and TGF-β signaling pathways regulates many complex developmental processes from the earliest stages of embryogenesis throughout adult life. In many situations, the two signaling pathways act reciprocally. For example, TGF-&
Tapan A. Shah, Melissa B. Rogers
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability.

open access: yesHereditas, 2009
Certain fluorescent DNA-binding compounds, among them quinacrine mustard and quinacrine, give characteristic banding patterns in human metaphase chromosomes; these patterns can be used to identify all the 24 chromosome types as well as chromosome ...
T. Caspersson, G. Lomakka, L. Zech
semanticscholar   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The genus Rubus (Rosaceae) in South Africa. IV. Natural hybridiza­ tion

open access: yesBothalia: African Biodiversity & Conservation, 1987
The genus  Rubus L. is represented in southern Africa by the subgenera  Eubatus Focke and  Idaeobatus Focke. A combination o f morphological data, data on the reproductive systems of some collections and meiotic chromosome behaviour indicates that a ...
J. J. Spies   +2 more
doaj   +1 more source

Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA [PDF]

open access: bronze, 2003
Pavel Vodic̆ka   +16 more
openalex   +1 more source

ISOLATED CHROMOSOMES [PDF]

open access: yesJournal of General Physiology, 1947
A E, Mirsky, H, Ris
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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